Study On The Distribution Law Of TCM Syndrome Types Of Hashimoto’s Thyroiditis

Objective:To establish the standard of Chinese Medicine(TCM)syndrome differentiation for Hashimoto’s thyroiditis,to lay the foundation for clinical guidance,further improvement of curative effect,and establishment of a comprehensive clinical curative effect evaluation system.Method:Search the database for documents that meet the inclusion and exclusion criteria,and screen a total of 50 related documents.The 50 selected documents were extracted for the elements of TCM syndromes,and 43 items were extracted.After consulting with experts,it was supplemented and revised,30 TCM syndrome elements were established,and Hashimoto’s thyroiditis TCM syndrome information collection form was formulated.Cluster analysis and principal component analysis of the obtained clinical data results form a syndrome differentiation model of Hashimoto’s thyroiditis.Combined with expert consultation in this field,the model was revised and the name of the syndrome type and the main and secondary symptoms were established.The elements of TCM syndromes were revised,Supplement,establish the clinical classification standard of Hashimoto’s thyroiditis.Analyze clinical biological indicators and clinical patient syndromes,and explore the relationship between the distribution of Hashimoto’s thyroiditis syndromes and objective indicators.Results:1.Research the elements of TCM syndromes in 160 clinical patients with Hashimoto’s thyroiditis,and draw the dialectical classification criteria for Hashimoto’s thyroiditis:(1)Liver depression and spleen deficiency syndrome: Main symptoms: neck swelling or large,foreign body sensation in neck Or obstructive feeling,emotional depression,good breathing,fullness or pain in the chest and thighs,full appetite,loose stools,fatigue and fatigue;secondary symptoms: female premenstrual breast pain,soft neck lumps,lethargy Tongue status: pale and dark tongue,fat and big,with tooth marks on the sides,thin white coating;pulse status: narrow pulse string(2)Syndrome of phlegm and blood stasis: main symptoms: neck swelling or enlargement,foreign body sensation or obstruction in the neck,phlegm in the pharynx;secondary symptoms:women with irregular menstruation,blood clots during menstruation,neck pain,breasts Block;Tongue condition: dark purple tongue,petechiae on the tongue,thin white or greasy coating;pulse condition: slippery or astringent pulse.(3)Syndrome of spleen and kidney yang deficiency: main symptoms: neck swelling or enlargement,sensation of foreign body or obstruction in neck,lack of energy,chills,cold limbs;secondary symptoms: heavy or swollen limbs,frequent nocturia,dry mouth Preference for warm drinks,tough neck lump texture,fatigue,lack of appetite;tongue picture: pale and dull tongue,big tongue body,thin and white fur;pulse state: pulse or sinking.(4)Yin Deficiency and Fire Excessive Syndrome: Main symptoms: neck swelling or large,foreign body sensation or obstruction in neck,irritability and sweating,irritability,illness often fluctuates with mood,soreness of waist and knees,dry mouth,preference for cold drinks;Secondary symptoms: heart palpitations,dry stools,poor sleep soundness,diminished hunger;tongue picture: red tongue,little tongue coating or yellow greasy tongue coating;pulse state: fine or stringy veins.Patients with clinical Hashimoto’s thyroiditis whose clinical symptoms meet 3 main symptoms,or 2 main symptoms,1 secondary symptom,or 1 main symptom and 2 secondary symptoms,and the same tongue coating and pulse conditions can be diagnosed with this syndrome type.2.Hashimoto’s thyroiditis patients with liver depression and spleen deficiency syndrome are younger than other syndrome types,with statistical differences(P<0.05),and TSH levels are higher than other syndrome types(P<0.05);HT Yin deficiency and fire prosperity syndrome TSH levels Compared with other syndrome types,there is a statistical difference(P<0.05).Conclusion:1.The syndrome differentiation of Hashimoto’s thyroiditis can be classified into four types: liver depression and spleen deficiency syndrome,phlegm and blood stasis mutual accumulation syndrome,spleen and kidney yang deficiency syndrome,yin deficiency and fire prosperous syndrome.2.Established the syndrome differentiation criteria for patients with Hashimoto’s thyroiditis.