Study On The Relationship Between Intra-abdominal Fat And Bone Mineral Density In Some Peri-Menopausal Women In Guilin

Objective(s)To analyze the current status of bone mineral density(BMD)and its influencing factors in peri-menopausal women aged 40-60 years who underwent physical examination in Guilin,and to explore the relationship between visceral fat and BMD in peri-menopausal women,so as to provide theoretical basis for the prevention and treatment of osteoporosis in peri-menopausal women.Method(s)From January 2020 to August 2022,perimenopausal women who underwent physical examination in the Health Management Center of the Affiliated Hospital of Guilin were selected as the research objects.Bone mineral density was measured by ultrasound bone mineral density meter,and visceral fat area was measured by body composition analyzer.The past history,dietary habits and lifestyle were collected by telephone questionnaire survey.The basic characteristics of the population,bone status and visceral fat status,and the relationship between them were analyzed.Result(s)1.A total of 330 peri-menopausal women were included in this survey,aged between 40 and 60 years,with an average age of 49.90±5.28 years.There were significant differences in age,education level,family history of diabetes and fracture,family history of fracture,vitamin D supplementation,calcium supplementation,menarche age,and mode of delivery(P < 0.05).2.The number of osteoporosis,osteopenia and normal bone mass were 18(5.45%),81(24.55%)and 231(70.00%),respectively.There was a significant difference in the distribution of bone status among women with different menstrual conditions(P< 0.05).There were 74(22.42%)patients with severe vitamin D deficiency,138(41.82%)patients with vitamin D deficiency,and 78(23.64%)patients with vitamin D insufficiency.3.There were significant differences in milk intake,calcium supplement,sunshine time and menstruation among women with different lifestyles(P < 0.05).4.In the comparison of different bone conditions,the average level of visceral fat area and the overall distribution of vitamin D levels in the examined women were statistically significant(P < 0.05).5.Milk intake,calcium supplement and sunshine time more than 30 minutes per day were protective factors for abnormal bone mass(P < 0.05).Age and menopause were risk factors for abnormal bone mass(P < 0.05).6.Vitamin D level was positively correlated with BMD.Visceral fat area was negatively correlated with BMD.Vitamin D level was positively correlated with BMD in the normal bone mass group,and weakly positively correlated with BMD in the osteopenia group.Conclusion(s)1.The detection rates of osteoporosis and low bone mass,vitamin D deficiency and insufficiency in peri-menopausal women in Guilin are similar to those in other regions.It is suggested that osteoporosis and bone mass in peri-menopausal women are serious,vitamin D supplementation should be increased,and health screening and management should be strengthened during this period.2.Age and menopausal factors are risk factors for abnormal bone mass and osteoporosis in peri-menopausal women.Milk intake,calcium supplement and sunshine time more than 30 minutes per day are protective factors for osteoporosis,but the calcium supplement rate is low in the study population.It is suggested that peri-menopausal women should pay attention to calcium supplement and milk intake in time,increase sunshine,and pay attention to menstruation.3,visceral fat area was negatively correlated with BMD.Vitamin D level was positively correlated with BMD.It is suggested that peri-menopausal women should pay attention to the monitoring and intervention of vitamin D level and abdominal obesity,especially the distribution of body fat composition.