Combination Of Sensation Control Soup And Oseltamivir Phosphate Granules In The Treatment Of Children Clinical Study Of Influenza B (Superficial Cold And Internal Heat Evidence)

Objective:To objectively evaluate the efficacy and safety of the treatment of children with type B influenza(superficial cold and internal heat evidence)by observing the TCM evidence points and symptom improvement time after the administration of sensitization control soup and oseltamivir phosphate granules,and to provide a basis for the combined treatment of type B influenza in children with Chinese and Western medicine.Methods:Seventy-six children aged 3-14 years in the pediatric fever clinic of Hospital were collected from August 2021 to December 2022 were collected and randomly divided into treatment and control groups.The control group was given oral oseltamivir phosphate granules + basic treatment,and the experimental group was given Sensation Control Soup on top of the control group,with a treatment cycle of 5days.The clinical efficacy of the combination of sensitization control soup and oseltamivir phosphate pellets was evaluated by statistical analysis of the data.Results:1.76 children were included in this study,3 cases were shed,73 cases were actually included,37 cases in the experimental group and 36 cases in the control group.2.The differences between the two groups before treatment were not statistically significant in terms of gender,age,epidemiology,TCM evidence score and body temperature(P > 0.05).3.Comparison after treatment(1)Overall efficacy: Total efficiency of the experimental group was 94.59% and the control group was 83.33%.The overall efficacy of the experimental group was better than that of the control group(P<0.05),the number of B flow conversions was more than the control group(P < 0.05).(2)Relief time of clinical symptoms: the experimental group required shorter time than the control group for remission of fever,chills,muscle aches,cough and sore throat(P < 0.05),and there was no difference between the two groups in the relief time of sputum,nausea and vomiting,nasal congestion,runny nose,dizziness and headache(P > 0.05).(3)TCM syndrome points after treatmentEvidence points:(1)The single evidence points were reduced after treatment,and the experimental group was more effective than the control group in improving fever,chills,muscle aches,cough,nasal congestion,runny nose and sore throat(P < 0.05);the two groups were comparable in improving sputum,headache,nausea and vomiting,and diarrhea(P > 0.05).(2)The total score of both groups will be lower than before treatment,within-group comparison,both groups were effective in treatment(P< 0.05);between-group comparison,the experimental group had better treatment effect than the control group(P < 0.05).(4)There was no statistically significant difference in the safety evaluation between the two groups(P>0.05).Conclusion: Experimental group and the control group were effective in the treatment of children’s type B influenza,but the experimental group could achieve better efficacy than the control group,which can be promoted in the clinic.