Clinical Observation On The Effect Of Modified Xiefei Decoction On Children’s Cough After Infection (Lung Heat Yin Injury Syndrome)

Objective:To observe the clinical efficacy and safety of xiefei decoction in the treatment of infective cough(lung heat Yin injury syndrome),further prove its unique advantages in children chronic cough,so as to better use in clinic in the future.Method:A total of 67 children who met the inclusion criteria of Traditional Chinese and Western Medicine were selected from the Children’s Outpatient Clinic of Affiliated Hospital of Chengdu University of Chinese Medicine and divided into treatment group and treatment group.control according to the random number table,with 33 cases in the treatment group and 34 cases in the control group lay.The treatment group received Chinese medicine oral lung decoction for diarrhea plus and minus,and the control group received western medicine oral montelukast sodium chewable tablets,and the treatment period was 14 days.Before the treatment,the children’s TCM symptom scores,TCM syndrome total scores and cough symptom visual simulation scores were recorded in detail,and the above points were recorded again after the treatment,and results were entered into statistical software for comparative analysis within and between groups were entered,and the clinical effectiveness of lung decoction for diarrhea plus treatment less cough(pulmonary fever-evidence of injury negative)in children after infection was assessed based on the results of the analysis.Results:1.General analysis of data: Before treatment,the sex,age and evolution of the two groups of children were compared and the results were P>0.05,the difference was not statistically significant and another comparison could be made.2.Prior to treatment,TCM symptom scores,global TCM syndrome score and visual analogue cough symptom score were compared.The result was P > 0.05,the difference was not statistically significant and further comparisons could be made.3.Scores of major and minor TCM symptoms:(1)Within-group comparison:After treatment,daytime and nighttime cough scores were compared between the two groups in the group,with statistical differences(P<0.01);after treatment,symptoms such as cough with sputum,dry throat and thirst,warm hands and feet,night sweats,lack of sleep and dry stools were compared in the treatment group and there were statistical differences(P<0.01);After treatment,the control group was compared to symptoms such as sputum and lack of sleep.There was a statistical difference(P<0.01);after treatment,the control group was compared within the group for symptoms such as dry throat and thirst,warm hands and feet,night sweats and dry stools,and there was no statistical difference(P> 0.05);(2)between groups: after treatment,scores for symptoms such as cough,sputum production,dry throat and thirst,and dry stools were compared between the two groups(P<0.01);After treatment,hand-foot fever and night sweat symptom scores were compared between the two groups.There was a statistical difference(P<0.05),and after treatment,nocturnal cough and insomnia scores between the two groups were compared between groups(P>0.05).4.TCM syndrome total scores:(1)Group comparison: After treatment,the medical syndrome total scores of the two groups were compared within the group and showed a statistical difference(P<0.01).(2)Between the groups: After the treatment,the total medical syndrome scores in the two groups were compared between the groups and showed a statistical difference(P < 0.01).5.Efficacy of TCM Symptoms: There was a statistical difference after treatment when comparing the overall efficacy rates of the two groups(P<0.01).6.Visual analogues of cough symptoms:(1)Within-group comparison: After treatment,visual analogues of cough symptoms in the two groups were compared within groups and found statistical differences(P<0.01).(2)Between groups: After treatment,the visual analogues of cough symptoms in the two groups were compared and statistically differentiated(P<0.01).7.Safety analysis: No side effects occurred in the treatment of the two groups,which suggests that the short-term safety of the two drug groups is good.Conclusion:1.The clinical effect of diarrhea pulmonary tonic plus minus(pulmonary fever negative injury detection)in the treatment of cough after infection in children is correct.2.In addition to the clinical effect of diarrhea lung decoction,the minuses such as cough,sputum production,dry thirst,warmth of the limbs,cold sweat,dry stools during the day are much better than montelukast sodium chewable tablets.3.The clinical effect of diarrhea,lung decoction and nocturnal cough and lack of sleep is comparable to montelukast sodium chewable tablets.4.Children had no side effects during treatment,and the safety of short-term clinical observation was good.