| Objective:Based on the theory of"nasal orifice opens the brain",the patients with qi deficiency and blood stasis evidence during the recovery period of ischemic stroke were treated with pharmaco-oxygen therapy to investigate the effects of pharmaco-oxygen therapy on their neurological recovery,quality of life,anxiety and depression.The aim was to provide a reference for the application of the theory of"nasal orifice and brain"to guide the prevention and treatment of ischemic stroke,and to explore appropriate medical care methods to improve the quality of life during the recovery period of ischemic stroke.Methods:Fifty cases of patients with Qi-deficiency and blood stasis evidence in the recovery period of ischemic stroke who met the criteria of this study were selected and divided into a test group and a control group according to the random number table method,with 25 cases in each group.The control group was treated with routine nursing,and the experimental group was treated with drug oxygen therapy on the basis of the control group,that is,30ml normal saline was completely dissolved for injection of Xuesaitong(freeze-dried powder)and placed in the ultrasonic atomizer,and the appropriate oxygen was vented through the oxygen intake hole.The two were mixed into sol and inhaled through the mask through ultrasonic atomization,and one end of the mask was connected with the bellows to exhaust the fog.One end was placed at the mouth and nose of the patient and oxygen flow was adjusted to 1.5～2 L/min,for 30 min.Before the intervention,10 days after the intervention,20 days after the intervention,and 30 days after the intervention,the patients in both groups scored on the Neurological Deficit Scale(CSS),Stroke-Specific Quality of Life Scale(SS-QOL),Ability to Take Care of Life Scale(ADL),Self-Assessment Scale for Anxiety(SAS),and Self-Assessment Scale for Depression(SDS),and the data were recorded and analyzed statistically.Results:1.comparison of general data:there were no significant differences between the two groups before the intervention in terms of age,gender,marriage,culture,work,past history,morbidity,whether they had received other previous treatment,health insurance and primary caregiver(P(29)0.05),which were comparable.2.Comparison of CSS scores:There were between-group effects(F=4.481,P<0.05),time effects(F=110.110,P<0.05)and interaction effects(F=4.693,P<0.05)for repeated measures ANOVA of CSS scores at different time points in the two groups.Between-group comparisons showed that before the intervention,there was no statistical difference in CSS scores between the two groups(P>0.05),and after the intervention at different time points,CSS scores in the test group were lower than those in the control group(P<0.05);within-group pairwise comparisons were statistically different(P<0.05),and CSS scores in both groups at different time points showed a decreasing trend.3.Comparison of SS-QOL scores:There was a between-group effect(F=12.623,P<0.05),time effect(F=523.275,P<0.05)and interaction effect(F=12.546,P<0.05)for the repeated measures ANOVA results of SS-QOL scores in both groups at different time points.Between-group comparisons showed that there was no statistical difference in SS-QOL scores between the two groups before the intervention(P>0.05),and after the intervention,SS-QOL scores were higher in the test group than in the control group at different time points(P<0.05);within-group pairwise comparisons were statistically different(P<0.05),and SS-QOL scores showed an increasing trend in both groups at different time points.4.Comparison of ADL scores:there were between-group effects(WaldX~2=12.554,P<0.05)time effects(WaldX~2=616.606,P<0.05)and interaction effects(WaldX~2=20.951,P<0.05);between-group comparisons showed no statistical difference in ADL scores between the two groups before and 10 days of intervention(P>0.05),and higher ADL scores in the test group than in the control group 20 days and 30 days after intervention(P<0.05);within-group pairwise comparisons were statistically different(P<0.05),and ADL scores in both groups at different The ADL scores of both groups showed an increasing trend at different points.5.Comparison of SAS scores:There were between-group effects(F=7.444,P<0.05),time effects(F=19.199,P<0.05),and interaction effects(F=3.438,P<0.05)for the results of the repeated measures ANOVA of SAS scores between the two groups;between-group comparisons showed that before the intervention,there was no statistical difference in SAS scores between the two groups(P>0.05),and after the intervention The SAS scores of the test group were lower than those of the control group at different time points(P<0.05);intra-group pairwise comparisons revealed that except for the control group,where there was no statistical difference between 10 days of intervention and pre-intervention(P>0.05),the SAS scores were statistically different between the two groups at different time points(P<0.05),and all SAS scores showed a decreasing trend.6.Comparison of SDS scores:There were between-group effects(F=6.391,P<0.05),time effects(F=179.819,P<0.05)and interaction effects(F=5.549,P<0.05)in the results of repeated measures ANOVA of SDS scores between the two groups;comparison between groups showed that there was no statistical difference in SDS scores between the two groups before the intervention,and at different time points after the intervention,the test The comparison between groups showed that before the intervention,there was no statistical difference in SDS scores between the two groups,and at different time points after the intervention,the test group had lower SDS scores than the control group(P<0.05);within-group comparison revealed that except for the control group,there was no statistical difference between 10 days of the intervention and before the intervention(P>0.05),other two comparisons between the two groups at different time points were statistically different,and the SDS scores all showed a decreasing trend(P<0.05).Conclusion:1.Pharmaco-oxygen therapy can promote the recovery of neurological function and improve the intervention effect in patients with Qi-deficiency and blood stasis evidence during the recovery period of ischemic stroke.2.Oxygen therapy can improve the ability of daily life and quality of life of patients with Qi-deficiency and blood stasis during ischemic stroke recovery.3.Oxygen therapy can relieve the negative emotions of anxiety and depression in patients with Qi-deficiency and blood stasis during ischemic stroke recovery and maintain psychological health. |
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