Analysis Of Influencing Factors Of Bone Mineral Density In Elderly Patients With Diabetes And Hypertension In A Community Of Taiyuan City

Objective:To study the relationship between bone mineral density(BMD)and blood glucose,blood pressure and related biochemical indicators in elderly patients with type 2 diabetes and hypertension in a community in Taiyuan,and to determine the effect of abnormal glucose metabolism and blood pressure on BMD in elderly patients with diabetes and hypertension.Methods:From January 1,2021 to December 1,2022,94 elderly patients with normal bone mass of type 2 diabetes mellitus(group A)and 107 patients with abnormal bone mass of type 2 diabetes mellitus(group B),97 patients with normal bone mass of hypertension(group C)and 101 patients with abnormal bone mass of hypertension(group D)registered in a community health service center in Taiyuan were collected.Compare the differences in biochemical indicators such as gender,age,BMI,liver and kidney function between Group A and Group B,and between Group C and Group D,and analyze the correlation between the related factors that have differences between the two groups and the bone mineral density of the lumbar spine(L1-4),left femoral neck,and left hip joint.Results:1.There was a statistical difference between the sex of normal and abnormal bone mass group in diabetes;FPG,Hb A1 c,TC in the abnormal bone mass group of diabetes were higher than those in the normal bone mass group,the difference was statistically significant;2.The correlation analysis in the first part of the study showed that gender was negatively correlated with bone mineral density of the lumbar spine,left femoral neck,and left hip joint,while FPG was only negatively correlated with bone mineral density of the left femoral neck,while Hb A1 c and TC were negatively correlated with bone mineral density of the left femoral neck,and left hip joint;Binary logistic regression analysis showed that gender was an independent influencing factor for bone mineral density of the lumbar spine,left femoral neck,and left hip joint,while TC was an independent influencing factor for bone mineral density of the left femoral neck,and left hip joint.3.There was a significant gender difference between the hypertensive group with normal bone mass and the hypertensive group with abnormal bone mass;The age,systolic blood pressure,and diastolic blood pressure in the hypertension group with abnormal bone mass were higher than those in the normal bone mass group,while AST,albumin,25(OH)D,and Ca were lower than those in the normal bone mass group.The difference between the two groups was statistically significant;4.The correlation analysis in the second part of the study showed that gender,age,systolic blood pressure,diastolic blood pressure,and BUN were negatively correlated with bone mineral density of the lumbar spine,left femoral neck,and left hip joint,while25(OH)D and albumin were positively correlated with bone mineral density of the lumbar spine,left femoral neck,and left hip joint,while AST was only positively correlated with bone mineral density of the left femoral neck;Binary logistic regression analysis showed that gender,systolic blood pressure,and diastolic blood pressure were independent influencing factors for bone mineral density of the lumbar spine,left femoral neck,and left hip joint.Age was independent influencing factor for bone mineral density of the lumbar spine,left femoral neck,and BUN was independent influencing factor for bone mineral density of the left femoral neck,and left hip joint.Conclusion:1.Gender and TC are negatively correlated with bone mineral density of left femoral neck and left hip joint in elderly patients with type 2 diabetes.Gender is an independent influencing factor of bone mass reduction in patients with type 2 diabetes.FPG,Hb A1 c,TC and bone mineral density in different parts are negatively correlated.The elderly female patients with type 2 diabetes should closely monitor FPG,Hb A1 c,TC and bone mineral density to minimize the risk of osteoporotic fracture.2.Gender,age,blood pressure,and BUN were negatively correlated with bone mineral density at three sites in hypertensive patients.Gender,age,and blood pressure were independent influencing factors for bone mass reduction in hypertensive patients.Albumin and 25(OH)D are positively correlated with bone mineral density at different sites.Elderly women with hypertension should actively control blood pressure,ensure the intake of protein and vitamin D preparations and calcium,closely monitor blood pressure and bone mineral density values,and minimize the risk of osteoporosis fractures.