| Objective:1.To construct a family nurse diet scheme based on the theory of family nurse dietary therapy,using the literature review method and expert meeting method,to provide a reference basis for disease prevention and treatment in patients with hyperuricemia.2.To explore the clinical application of the family nurse diet therapy program in patients with hyperuricemia and to verify the feasibility and effectiveness of the diet therapy program,with the aim of improving serum uric acid,blood glucose,lipids,liver and kidney function and related metabolic co-morbidities in patients with hyperuricemia.Methods:1.Construction of a dietary therapy program for family nursesThe literature review method and expert meeting method were applied to construct the home nurse diet therapy program.We systematically searched domestic and international databases and relevant guideline websites for the treatment guidelines and disease-related research advances of hyperuricemia and gout for the period from the establishment of the database to March 31,2021,extracted the relevant contents of the guidelines and expert consensus on the dietary treatment of patients with hyperuricemia,and conducted a preliminary construction of a dietary therapy protocol for patients with hyperuricemia suitable for our local population,and then revised the draft using the expert meeting method.In turn,the home nurse diet regimen was determined.2.Short-term clinical empirical study of a family nurse diet for patients with hyperuricemia using prospective research73 patients with hyperuricemia were recruited and randomly divided into 36 cases in the tea group and 37 cases in the therapeutic diet group,in the end,a total of 60 patients completed the experiment completely.The tea group used buckwheat tea combined with health education,and the food therapy group implemented a home nurse diet therapy intervention program based on the tea group,comparing the two groups of patients with and without differences in serum uric acid,blood glucose,blood lipids,liver and kidney function and other indicators.Results:1.In the construction of the food therapy program for family nurses,members of the research team selected the contents of the diagnosis and treatment guidelines,expert consensus and dietary guidance for hyperuricemia disease through literature search,and initially formulated the food therapy program after group discussion;an expert meeting was held to validate the program,and the authority coefficient of experts was 0.85,indicating that the opinions of experts have high authority and credibility.Finally,combining the opinions and suggestions of 12 experts in professional fields,the preliminary formulated food therapy program was modified and determined,and a consensus was reached to form the family nurse food therapy program.2.Short-term clinical empirical results:(1)This study ultimately recruited 73 patients and randomly divided them into a tea drinking group of 36 cases and a dietary therapy group of 37 cases.During the entire study period,2 cases in the tea drinking group voluntarily withdrew and 4 cases were lost to follow-up;One case in the dietary therapy group was lost to follow-up,four cases were unable to withdraw due to the epidemic,and two cases were excluded.In the end,a total of 60 subjects from both groups completed the experiment.There was no statistically significant difference in baseline data such as age,gender,weight,BMI,course of disease,serum uric acid,blood glucose,blood lipids(TC,TG,LDL-C,HDL-C),liver function(ALT,AST),kidney function(Cr,BUN),smoking,drinking,and dietary habits between the two groups of subjects.(2)Short term clinical empirical results:(1)serum uric acid: UA decreased after the intervention of both groups,the UA of tea drinking group decreased from 464.29±54.26 to 457.53±53.07,and the UA of buckwheat tea plus diet therapy group decreased from472.35±34.57 to 419.07±40.38,and the difference between the two groups was statistically significant(P <0.05);After the intervention,buckwheat tea plus diet group had a significant efficacy in 11 cases(36.67%),effective in 13 cases(43.33%),and ineffective in 6 cases(20.00%),with a total effective rate of 80.00%;After the intervention,tea drinking group had 0 cases(0.00%),effective 9 cases(30.00%),21(70.00%)ineffective,and the total effective rate was 30.00%,and the UA efficacy of buckwheat tea plus diet therapy group was better than that in tea drinking group,and the difference was statistically significant(P<0.05).(2)Weight: The weight of subjects in buckwheat tea plus diet therapy group decreased from 75.13±10.43 kg to 70.77±10.18 kg after the intervention,the difference was statistically significant(P<0.05);the weight of tea drinking group decreased slightly compared with before the intervention,and the difference was not statistically significant(P>0.05),and the difference between the two groups was statistically significant(P <0.05)。(3)Biochemical indexes: TC,TG,LDL-C,FPG,ALT,AST,Cr,BUN decreased after the intervention of buckwheat tea plus diet therapy group compared with before intervention,HDL-C increased compared with before intervention,and the intra-group comparison difference was statistically significant(P<0.05);TC,TG,LDL-C,FPG,Cr,BUN decreased in tea drinking group compared with before intervention,but there was no significant difference in TG,HDL-C,and BUN group(P> 0.05).The differences between the two groups were statistically significant(P<0.05)between the two groups: LDL-C,FPG,ALT,AST and Cr were significantly(P<0.05);the differences between TC,TG,HDL-C and BUN were not statistically significant(P>0.05).Conclusion:The family nurse diet scheme based on the family nurse diet theory has a good effect on weight loss and improvement of related metabolic indexes for overweight or obese patients with hyperuricemia,which confirms that the theory has certain validity. |
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