Clinical Study On Acupuncture Treatment Of Freezing Of Gait In Parkinson’s Disease With Qi And Blood Deficiency

Objective:Based on the conventional treatment with Western medicine,this study explores the treatment of patients with Qi and blood deficiency Parkinson’s Disease(PD)with Freezing of Gait(FOG)with acupuncture,and analyzes the clinical efficacy of related movement symptoms and frozen gait symptoms in PD with FOG.To provide a new idea of traditional Chinese medicine for the quality of life of PD patients with FOG.Methods:Seventy patients with Parkinson’s disease and frozen gait who were hospitalized or outpatient in Neurology Department of Jiangxi Provincial Hospital of Integrated Traditional Chinese and Western Medicine from October2021 to January 2023 were selected,and 70 patients with PD and FOG who met the inclusion criteria were randomly divided into treatment group and control group,with 35 patients in each group,for a 2-week clinical observation study.The control group maintained the original dose of conventional Western medicine treatment,and the treatment group was combined with acupuncture on the basis of conventional Western medicine treatment.Acupuncture was selected as DU20,、EX-HN1、DU16、DU14、 bilateral GB20、LI4、LR3、LI11、RN6、SP10、ST36、SP6、GB34、BL18 、BL23.General data(age,sex,course of disease,Hoehn-Yahr(correction)staging)of the control group and the treatment group were analyzed before and after treatment,as well as Part III of the Movement Disorder Society Sponsored Revision of the Parkinson’s Disease Rating Scale the Unified Parkinson’s Disease Rating Scale III,MDS-UPDRS III,Freezing of Gait Questionnaire(FOGQ),Finally,SPSS26.0 statistical software was used to analyze the collected data.Results:1.Comparison of baseline data: Baseline differences in age,gender,course of disease and Hoehn-Yahr(correction)grade were not statistically significant between the two groups(P > 0.05);There were no significant differences in UPDRS III scores and FOGQ scores at baseline between control group and treatment group(P > 0.05).2.Efficacy analysis of clinical scales:(1)UPDRS III scores and FOGQ scores of patients in the treatment group after 2 weeks of acupuncture treatment were significantly lower than those before treatment,with statistical significance(P < 0.05);There were no significant differences in UPDRS III scores and FOGQ scores in the conventional western medicine group after 2 weeks(P > 0.05).(2)The patients in the treatment group were followed up 2 weeks after the end of acupuncture treatment.The UPDRS III score of the treatment group was still significantly different from that before treatment(P < 0.05),and the FOGQ score was not significantly different from that before treatment(P > 0.05).The UPDRS III scores and FOGQ scores were not significantly different after 2 weeks of follow-up in the group of conventional western medicine compared with those before treatment(P > 0.05).Conclusion:On the basis of conventional Western medicine treatment,acupuncture treatment can improve tremor,muscle rigidity,leg flexibility,posture maintenance,frozen gait and other gait disorders in patients with Parkinson’s disease accompanied by frozen gait.The curative effect after treatment and2 weeks after completion of treatment were significant,and no adverse events occurred.Acupuncture treatment can improve the single symptom of frozen gait in PD patients with FOG,which has a significant effect after treatment,but no significant effect after 2 weeks of follow-up.The long-term clinical effect still needs to be further explored by clinicians,which may be related to the short treatment time and limited number of samples in this study.Acupuncture in the treatment of PD with FOG is safe and reliable,and has significant clinical effect and potential clinical value.