Study On The Effect Of Metabolic Bariatric Surgery On Patients With Metabolic Syndrome In Part Of Inner Mongolia

Objective:To explore the initial conditions of patients with metabolic syndrome in part of Inner Mongolia and the effect of metabolic bariatric surgery on metabolic syndrome.Methods:From 2016 to 2022,in part of Inner Mongolia Region,patients who underwent metabolic bariatric surgery for metabolic syndrome were retrospectively analyzed.The patient’s body weight,body mass index(BMI),percentage of excess weight loss(EWL%),blood glucose,blood lipid,uric acid and other related metabolic indicators were collected before surgery and 1,3,6,and 12 months after surgery.Body weight and metabolic disease remission were analyzed statistically.Results:(1)Medical records of 82 patients were collected according to inclusion and exclusion criteria,including 65 cases from Inner Mongolia People’s Hospital,12 cases from Baotou Sinopharm North Hospital,and 5 cases from Bayannur Hospital.The follow-up time was 1 year,including 10(12.2%)males and 72(87.8%)females,with average BMI of(39.39±6.71)kg/m~2.There were 22(26.8%)patients with type 2 diabetes mellitus,77(94%)non-alcoholic fatty liver disease,20(27.8%)patients with polycystic ovarian syndrome,18(22%)patients with obstructive sleep apnea syndrome,49(59.7%)patients with hyperuricemia,and 33(40.2%)patients with hyperlipidemia before surgery.22(26.8%)patients with hypertension;78 cases(95.3%)underwent laparoscopic sleeve gastrectomy and4 cases(4.7%)underwent laparoscopic single anastomotic gastric bypass.(2)All patients successfully completed the operation without conversion to open surgery,intraoperative massive bleeding and death.The average operative time was(147.8±41.1)min,the average intraoperative blood loss was(19.17±5.20)ml,and the average postoperative hospital stay was(3.5±1.0)days.Early postoperative complications were 7(8.5%)cases,including 1 case of postoperative intestinal leak caused by Trocar injury,which was determined to be Clavien-DindoⅢb,and recovered after reoperation.1 case of postoperative pneumonia was recovered after anti-inflammatory treatment.5 cases of Trocar hole infection were recovered after active dressing change.postoperative long-term complications were 9(10.9%)cases,4 cases of iron deficiency anemia.1 case of Anastomotic ulcer;4 cases of Biliary sludge deposition.(3)There were statistically significant differences in the body weight,BMI,abdomen circumference,hip circumference,EWL%,fasting blood glucose,glycated hemoglobin,pancreas islet function,liver and kidney function,and blood lipid with the first year after surgery compared with preoperative(P<0.05).There was statistically significant differences in nonalcoholic fatty liver disease whose incidence decreased from 94%preoperatively to 69.5%postoperatively(P<0.05).There was statistically significant differences in polycystic ovary syndrome whose incidence decreased from 27.8%preoperatively to 7%postoperatively(P<0.05).There was statistically significant differences in obstructive sleep apnea hypopnea syndrome whose incidence decreased from 22%preoperatively to 3.7%postoperatively(P<0.05).There was no statistically significant differences in hypertension whose incidence decreased from 26.8%preoperatively to 18.3%postoperatively(P=1.919).Conclusion:Metabolic bariatric surgery is a safety and effective weight loss program,which can completely or effectively remission diabetes,polycystic ovary syndrome,obstructive sleep apnea hypopnea syndrome,hypertension,nonalcoholic fatty liver disease,dyslipidemia and other metabolic diseases.