Clinical Guidance Value Of Contrast-enhanced Ultrasound Combined With Quantitative Analysis Of Parameters And Elastography In The Diagnosis Of Active Inflammatory Bowel Disease

Objective: Study the diagnostic effect of combined use of contrast-enhanced ultrasound(CEUS)and quantitative analysis parameters on inflammatory bowel disease(IBD)with inflammatory activity,and the significance of elastic imaging parameter values in distinguishing the nature of intestinal wall stenosis.Methods: A total of 53 inpatients of IBD in the Department of Gastroenterology and outpatient follow-up patients of the First Affiliated Hospital of Bengbu Medical College were selected for admission from November 2021 to December 2022.Combined with pathological and clinical diagnosis,the two groups were divided into ulcerative colitis(UC)and Crohns disease(CD)groups.According to the CD activity index rating scale and the modified Mayo scale,the two groups were divided into active and inactive groups respectively.Then compare the thickness of the intestinal wall between the active and inactive groups,power Doppler image(PDI)blood flow,CEUS intensification pattern and quantitative parameters [peak intensity(PI),ascending slope(AS),arrival time(arrival)time,AT),time to peak(TTP)] and comparison of Emax values of Young’s modulus between fibrous stenosis and inflammatory stenosis in patients with inflammatory bowel disease.Results: Intestinal wall thickness in 2 groups of IBD patients,PDI in UC group,CEUS enhancement pattern and quantitative parameter PI in 2 groups of IBD patients,AT in UC group and TTP in CD group were significantly different between active and inactive groups(P<0.05).The elastic imaging values of UC group and CD group were significantly different between intestinal wall inflammatory stenosis and fibrous stenosis,the difference was statistically significant(P<0.05).Conclusion: Intestinal wall thickness,PDI,CEUS enhancement mode,and quantitative parameters PI,AT,TTP are all related to the diagnosis and evaluation of inflammatory bowel disease activity.The value of Young’s modulus Emax has a certain significance in predicting the nature of intestinal wall stenosis.