Study On The Medication Rule Of Traditional Chinese Medicine For Coronary Microvascular Disease Based On Data Mining Technology

Objective:In this study,using Internet data mining technology guided by the theory of "" Qimai Chang Tong "",the rules of traditional Chinese medicine(TCM)use in the treatment of coronary microvascular disease are collated,analyzed,summarized and summarized.And to verify the feasibility of the ""Qimai Chang Tong "" disease mechanism theory for clinical treatment and to provide a reference for clinical TCM treatment of coronary microvascular disease.Methods:Combined with manual and computer search,acquisition and retrieval Chinese knowledge net,Wanfang Data knowledge service platform,vipu Chinese science and technology journal database,and US National Library of medicine journals literature search database were searched for relevant clinical studies on TCM treatment of coronary artery microvascular disease published from the databases until December 31,2022,and the literatures eligible for inclusion were manually screened and data collated,Association rule analysis was performed with spssmodeler18 software,and clustering analysis was performed with SPSS statistics 22 software to summarize the prescription rules of traditional Chinese medicine(TCM)for the treatment of coronary microvascular disease.Results:A total of 428 literatures were obtained,following the relevant inclusion and exclusion criteria,and finally,a total of 80 herbs were selected,involving 125 herbs of traditional Chinese medicine,and the cumulative frequency of medication was 699 times.(1)The high-frequency herbs are Danshen,chuanxiong,Huangqi,Danggui,Gancao,safflower,Panax ginseng,Panax notoginseng,macrostemonostemonous and guar and other medicines;(2)The efficacy of traditional Chinese medicine(TCM)is frequently based on toning deficiency,invigorating blood and regulating qi;(3)The medicine four Qi was used most for temperature,cold,and flat,while five flavor was mainly Gan,bitter,and Xin;(4)The most prescribed medicines include liver,heart,and lung meridian;(5)Association rule results support degree the top 5 drug pairs are "" Danshen Huangqi "","" Danshen Chuanxiong "","" Chuanxiong Huangqi "","" Chuanxiong Honghua "" and "" Chuanxiong Danggui "",etc;(6)There were four clusters identified by high-frequency cluster analysis,which were as follows:guar,macrostemonostem,safflower,peach Ren,chuanxiong,Chishao,Huangqi,Danshen and Panax notoginseng;Banxia,oyster,Codonopsis pilosula,Coptis chinensis;Guizhi,Bai Shao,Danggui,Dihuang,Chaihu,citrus aurantium,Gancao,Poria,tulip gold;Panax ginseng,Ophiopogon japonicus.Conclusion:The commonly used medicines in traditional Chinese medicine(TCM)for the treatment of coronary microvascular disease are as follows:Danshen,chuanxiong,Huangqi,Danggui,Gancao,Honghua,Panax ginseng,Panax notoginseng,macrostemonosa and guarou,etc;The traditional Chinese medicine(TCM)categories mainly include invigorating deficiency,invigorating blood circulation and eliminating stasis,and regulating qi.Four Qi is used most abundantly for warmth,cold,and flat,while five taste is mainly Gan,bitter,and Xin,and the classic is mainly GUI Gan,heart,lung,and spleen meridians.The basic remedy is to invigorate Qi and strengthen deficiency,and invigorate blood and eliminate stasis.It is in accordance with the treatment idea of "" Qinai Chang Tong "" disease mechanism theory.