Clinical Observation On The Treatment Of Depression Comorbidity And Insomnia By Acupuncture Combined With Wheat-Grain Moxibustion Based On The Theory Of Treating Both Heart And Gallbladder

Objective: On the basis of taking western medicine,to observe the clinical efficacy of acupuncture combined with wheat-grain moxibustion under the guidance of the theory of simultaneous treatment of heart and gallbladder in treating depression complicated with insomnia,and to explore a better scheme of acupuncture and moxibustion for treating this disease.Methods: A total of 60 patients with depression and insomnia who met the inclusion criteria were randomly divided into control group and observation group.The control group was treated with agomelatine tablets,25 mg/ time,1 time/day.The observation group: based on the control group,acupuncture for heart and gallbladder combined with wheat-grain moxibustion was applied.Firstly,acupuncture was applied to Baihui(GV 20),Yintang(GV29),Fengchi(GV 20),Shenmen(GV 20),Hegu(LI 4),Taichong(GV 24)and Yanglingquan(GB 34),and the needles were retained for 30 min.Wheat-grain moxibustion was applied at Xinshu(BL 23)and Danyu(BL 23),3 cones at each acupoint.Treatments were given every Monday,Wednesday and Friday.Both groups were treated for 3 consecutive courses of 4 weeks as a course of treatment.Evaluation: The patients were followed up at 0,4,8,12 weeks of treatment and 8 weeks after the end of treatment.Hamilton Depression Scale-17(HAMD-17)score and Pittsburgh Sleep Quality Index(PSQI)and World Health Organization quality of life-BREF(WHOQOL-BREF)were used to evaluate the clinical efficacy.The Side Effects and safety were evaluated by Rating Scale for Side Effects(SERS)score and acupuncture related safety.SPSS 17.0 was used to analyze the relevant data.Results: 1.Before treatment,there was no statistically significant difference in the general condition,HAMD-17,PSQI,and WHOQOL-BREF scores of the two groups of depression comorbidity insomnia patients(P > 0.05),which was comparable.2.The clinical efficacy of the two groups of patients with depression and insomnia: the observation group was better than the control group(P <0.05).3.Comparison of HAMD-17 scores after treatment: Compared with 0weeks of treatment,HAMD-17 scale scores of 4 weeks,8 weeks,12 weeks of treatment and follow-up period were decreased in both groups(P < 0.05);After 8 weeks and 12 weeks of treatment,scores of both groups were lower than those of the previous course(P < 0.05);During the follow-up period,there was no significant difference in scores between the two groups compared with the previous treatment course(P > 0.05).Compared with the control group at the same time point,HAMD-17 scores in the observation group were significantly decreased at each evaluation point(P < 0.05).4.Comparison of PSQI scores after treatment: intra-group comparison:compared with 0 week of treatment,the PSQI scores of the observation group were decreased at 4 weeks,8 weeks,12 weeks of treatment and follow-up period(P < 0.05).There was no significant difference in PSQI score in the control group after 4 weeks of treatment(P > 0.05),while PSQI scores decreased at 8 weeks,12 weeks and follow-up(P < 0.05);After 8 and12 weeks of treatment,the scores of the two groups were lower than those of the previous course(P < 0.05);During the follow-up period,there was no significant difference in the scores of patients in the observation group compared with the previous course(P > 0.05),while the score of the control group was significantly higher than that of the previous course(P < 0.05).There was no significant difference in PSQI scores between the two groups after 8 weeks of treatment(P > 0.05);Compared with the control group at the same time points,the observation group decreased more significantly at4 weeks,12 weeks and follow-up(P < 0.05).5.Comparison of WHOQOL-BREF scores after treatment: intra-group comparison: compared with 0 week of treatment,the WHOQOL-BREF scores of the two groups were significantly increased at 4 weeks,8 weeks,12 weeks of treatment and follow-up period(P < 0.05);After 8 and 12 weeks of treatment,the WHOQOL-BREF scores of the two groups were higher than those of the previous course(P < 0.05).Compared with 12 weeks of treatment,the WHOQOL-BREF in the observation group was increased during the follow-up period(P < 0.05),while the scale score in the control group was significantly decreased(P < 0.05).Compared with the control group at the same time point,the scores of the observation group at each evaluation time point were significantly higher than those of the control group(P < 0.05).6.Adverse reactions: The median SERS score of patients in the observation group was 0,and the median SERS score of patients in the control group was 4;Adverse reactions in the observation group were significantly lower than those in the control group(P < 0.05).Conclusion: In this study,on the basis of oral western medication,acupuncture combined with wheat-grain moxibustion based on the theory of heart and gallbladder treatment has better short-term and long-term efficacy than simple western medication in the treatment of depression and insomnia,and the curative effect is lasting and stable,and it can reduce the adverse reactions of medication,effectively improve the symptoms of depression and insomnia,improve the quality of life of patients,which has clinical promotion value.