Study On The Relationships Between "Disease-Syndrome-Symptom-Chinese Medicinal Material-Dosage" In Fu Qing-zhu Nvke

Objective:To complete a systematic study of the Relationships between "Disease-Syn-drome-Symptom-Chinese Medicinal Material-Dosage" in Fu Qing-zhu Nvke,and further explored the theoretical connotations of Chinese medicine contained in the study results,with a view to providing reference for modern clinical practice.Method:Using the literature method,data statistics method,taxonomy method and theoretical analysis method,make a bibliometric and visual analysis of the modern related research of Fu Qing-zhu Nvke,summarize the previous research situation,find the shortcomings and design the research scheme according to the shortcomings.the main research object was Fu Qing-zhu Nvke.The data information involved was standardized,the literature data set of Fu Qing-zhu Nvke was established,and the single-level data analysis of disease category,disease name,evidence type,symptom,prescription and medicine was conducted respectively with the help of the TCM inheritance computing platform V3.0 software;for the quadruple data of"Disease-Syndrome-Symptom-Chinese Medicinal Material" and"Syndrome-Symptom-Chinese Medicinal Material-Dosage",the data were statistically and filtered with the help of Excel,and combined with the TCM inheritance computing platform V3.0 software The data of the quadruplet of"Disease-Syndrome-Symptom-Chinese Medicinal Material-Dosage" were statistically and filtered by Excel and analyzed by combining with the TCM heritage computing platform V3.0.The above literature data sets were visualized and analyzed to express the data and research results.Finally,based on the theoretical knowledge of TCM and the research results of the dataset,two characteristics of the Relationships of"Disease-Syndrome-Symptom-Chinese Medicinal Material-Dosage" in Fu Qing-zhu Nvke were found,namely,the characteristics of the treatment method and the characteristics of the medicinal properties of the medicine used,in which the characteristics of the treatment method serve as the inner line connecting the Relationships of "Disease-Syndrome-Symptom-Chinese Medicinal Material-Dosage"in Fu Qing-zhu Nvke and the inner line of the Relationships of"Disease-Syndrome-Symptom-Chinese Medicinal Material-Dosage".The characteristics of the treatment method as the inner line connecting the Relationships of "Disease-Syndrome-Symptom-Chinese Medicinal Material-Dosage" and the characteristics of the medicinal properties of medicine embody certain regularity,so they are discussed and summarized.Results:This study mainly includes the establishment of a dataset of the literature on"Disease-Syndrome-Symptom-Chinese Medicinal Material-Dosage" of Fu Qing-zhu Nvke,the visualization of the results of the dataset,and the discussion of Chinese medicine theory based on the results of the dataset.1.Bibliometric and Visual Analysis on the Related Studies of Fu Qingzhu Nvke:Summarize the research status,research hotspot and prediction development trend of Fu Qingzhu Nvke.Retrieving the relevant research contents of Fu Qingzhu Nvke on CNKI in the past 40 years,Using CiteSpace 5.8.R3 software for bibliometric analysis,visual display and analysis are carried out from the aspects of publishing institutions,authors and keywords.Results:After screening,685 papers were finally included.The research stage was divided into three stages:1983-2000,2001-2014,and 2015-2022.The most researchers in each stage were Jin Chun,Wang Xin,and You Zhao.Ling,Liu Yanfeng;Liaoning University of Traditional Chinese Medicine,Hunan University of Traditional Chinese Medicine,and Chengdu University of Traditional Chinese Medicine are the most research institutions in the three stages in turn.The researchers and research institutions have gradually changed from independent research to cooperative research;keyword analysis shows that Fu Qingzhu Nvke The research of"Gynecology" mainly focuses on the direction of gynecological diseases,with the research on dysmenorrhea,vaginal discharge,and infertility as the highest,followed by the research on the law of syndrome and treatment and the law of medication,which has already involved the study of dosage.Conclusions:The map intuitively shows the research situation of Fu Qingzhu Nvke for nearly 40 years from 1983 to May 30,2022.Through three different stages of presentation,it is found that the research hotspots of Fu Qingzhu Nvke are often consistent with the current Western gynecology.Disease research that attaches importance to practicality,and research with the help of modern new methods and new technologies is gradually increasing,but there are many scattered researches,and the research results cannot be shared.It is necessary to further strengthen the cooperation between authors and institutions to realize the transformation of research results.2.The results of the visualization study of the literature dataset of Fu Qing-zhu Nvke:On the basis of the data set,this study analyzed and obtained the research results of two plate data sets,which are the results of the relationships between the single-level data of the first plate and the multi-level data of the second plate.The results of single-level data in the first section:including five aspects:disease,syndrome,symptoms,medication and dosage effect.Disease:involving 50 name of traditional Chinese medicine,including high frequency name 10,in turn,infertility,collapse,leakage,postpartum disease,childbirth,prenatal,prenatal,restless,menstrual syndrome,dysmenorrhea,ghost,with too much,the collapse is divided into collapse and leakage,and collapse and collapse of the same frequency,so here only in the collapse.50 TCM names were classified,and five categories of gynecological diseases were obtained.According to the proportion of Fu Qing,the proportion was menstrual diseases,labor diseases and postpartum diseases,fetal pregnancy diseases,female miscellaneous diseases and complicated diseases.In terms of syndrome type:a total of 96 syndrome types are involved,and 18 combined syndrome types are involved,among which there are 9 high-frequency syndrome types,in order,which are:blood syndrome,qi deficiency syndrome,qi depression syndrome,fine deficiency syndrome,Yin deficiency syndrome,qi withdrawal syndrome,Yang deficiency syndrome,wet turbidity syndrome,and strange classics syndrome.Among them,qi deficiency syndrome is mostly manifested as temper deficiency,including 96 syndrome and temper qi depression syndrome,but the frequency of qi depression syndrome and liver qi stagnation syndrome is the same,which can indicate that both appear together,and qi depression syndrome must be accompanied by liver qi stagnation syndrome.Symptom:The original text of Fu Qing-zhu Nvke involved scattered and numerous symptoms.In this study,24 symptoms were classified through the common characteristics between symptoms,among which the frequent symptoms were pain,abnormal mental emotion,vaginal bleeding,and abnormal metabolism of body fluid operation.Medication:①Fu Qing-zhu Nvke drug four qi mainly temperature,accounting for 44%,followed by cold,flat,less use of cold medicine.②In the five tastes to sweet,bitter only second,sweet and bitter,less use of acid,salty drugs.③Mainly to the lung,heart,spleen meridian.④According to the efficacy category,the deficiency drugs are large,accounting for more than 50%.Measurement and effect:Angelica blood tonic reuse 1 two,With 5 qian is intended to promote blood circulation and blood,With 2 qian mainly to assist temper and micro blood;Ginseng reuse 2 two cases of tonic to help blood,fetus,asthma stop,Use 1 qian to slightly replenish qi to relieve depression and remove blood stasis,With 1 two qi and solid,qi and lung,With 3 qian yiqi peace of god,yiqi nourishing Yin;atractylodes reuse 2 two big spleen and stomach qi,So as to help the gas lift to fixed photography;White peony root Reuse 1 two mainly to fill the liver blood to relieve depression,phlegm dampness,blood diversion,Light use of 2 qian to nourish the liver and blood drop gas reverse;Familiar rehmannia reuse 2 two can fill the governor,Light use of 3 points can still tonify the kidney essence and can help the liver nourishing the blood solution depression,Commonly used 1 two to nourish kidney to nourish Yin;Peony skin used to 3 qian to play its work in promoting blood circulation and removing blood stasis,With 1 two main start blood stasis,Besides the function of the disease,With 5 qian mainly to set the mind,cool bone steaming and meridian effect;The reuse of Astragalus 2 is intended to replenish the temperature with the help of its temperature,Blood metaplasia,Need to benefit water swelling can be light use 3 qian;Chuanxiong light use to 1 qian can be a lack of blood tonic,If the acute under the blood stasis need to reuse to 1 two;Reuse porcocos 1 two main water swelling,Light use of 1 qian owner to open the downward channel.The second plate is the study of multi-level data relationship:including the study of"disease-syndrome-disease-drug" relationships and the study of"syndrome-disease-drug-quantity" relationship."Disease-disease-disease-drug" relationship is:①menstrual disease category for"blood collapse" and "classics",involving the syndrome mainly for blood deficiency syndrome,blood cold syndrome,blood stasis syndrome,and kidney Yin deficiency syndrome,gas depression,for the records of disease symptoms mainly have vaginal bleeding abnormalities,abnormal menstrual cycle,menstrual volume abnormal,menstrual before and after the syndrome.Drug selection of ginseng,is flexible compatibility,with the help of ginseng into gas and blood performance can be widely associated with drugs.②The category of belt disease belongs to the "belt next",mainly for wet,heat type related,with abnormal quantity,color,taste,and accompanied by pain,thirst,stomachache,swelling and other types of heat,body fluid operation adverse symptoms.The selection of medicine,know mother,yellow cypress,Coptis chinensis,wine,fried seeds,gardenia,venus and Chen,calcined gypsum and other nourishing Yin and fire,water and wet products.③ The category of fetal pregnancy diseases is included in the "ghost fetus section","pregnancy section" and"miscarriage section",in addition to the general gas deficiency syndrome,blood deficiency syndrome,gas depression syndrome,but also often manifested as hot syndrome,and more accompanied by pain symptoms.In addition to the conventional set four things soup,but also clever application of Fried sand kernel,commonly used for the liver or stomach function imbalance,such as liver qi soup,spleen and stomach qi deficiency,with soil not only can use the pain,but also through the stomach and liver and solution depression;hot syndrome is used for water and fire,reuse rehmannia,such as burning tire soup,gas soup.④The category of postpartum disease is included in the "difficult labor","positive birth" and "postpartum",mainly manifested as blood deficiency syndrome,often accompanied by organ sagging symptoms.Nourishing qi and raising qi are used together with blood tonic and promoting blood circulation drugs,using qi tonic products,such as ginseng,Atractylodes tyloand Astragalus,and the use of Chuanxiong with promoting blood circulation.⑤The category of female miscellaneous diseases is included in the"infertility",mostly Yang deficiency syndrome type,mostly accompanied by obesity,stuffy swelling and acute symptoms,commonly used to make pinellia pinellia,penta,psorolien.In the case of "syndrome-disease-drug-quantity" relationship,because there are many syndrome types and limited time,this study mainly studies the relationship of high-frequency syndrome type data.Through screening,five high frequency syndrome types,namely blood syndrome,qi deficiency syndrome,qi depression syndrome,fine deficiency syndrome and Yin deficiency syndrome.Specific results are:①this study reference the TCM clinical diagnosis and treatment term syndrome part through the blood abnormalities,blood function,blood running abnormal three aspects of the fu qing main female in all blood syndrome class type summarized,found that fu qing main female about blood syndrome class has more accurate positioning,qualitative thought.Blood syndrome drugs appear most frequently,the dosage is mainly 3 qian,5 qian,1 two,2two.Often used angelica with ginseng,mostly used in the accompanying pregnancy state and postpartum stage,as well as pain,abnormal mental mood,abnormal body fluid metabolism and abnormal color symptoms.②Gas deficiency syndrome has the highest frequency of use of ginseng,and the common dosage is 3 yuan,5 yuan,12,22 yuan.Often with ginseng with angelica,atractylodes is used for abnormal body fluid metabolism,stomach discomfort,pain,pregnancy,postpartum.③Gas depression syndrome in the highest frequency of use is angelica,common dosage for 3,4,5,6 qian,1 two,often compatible with white peony root,or atractylodes for pain,abnormal spirit,abnormal body fluid operation,before and after menstruation,thin body thin,abnormal color,fetal leakage,fetal abortion,fetal movement.④In the essence loss syndrome,the highest frequency of medication is ripe Rehmannia and dogwood,among which ripe Rehmannia is 1 liang,dogwood is 3 yuan,5 yuan,5 yuan more qian.In different symptoms,when pain symptoms,cooked rehmannia and dogwood are used together;when abnormal mood and jujube kernel are used;when vaginal bleeding is used.⑤In Yin deficiency syndrome,the highest frequency of medication is ripe Rehmannia rehmannia,followed by dogwood,in which the dosage of cooked Rehmannia is 12,16 liang(pills),5 yuan,3 yuan,dogwood 5 yuan,10 liang(pills)and 2 yuan.In different symptoms have the corresponding main medicine,when vaginal bleeding,with mulberry leaves,notoginseng powder more;in infertility,with dogwood 5 qian.3.Based on the theoretical summary of the relationship between"disease-syndrome-disease-drug-quantity" in Fu Qing-zhu Nvke:Through the theoretical summary of the relationship between"disease-syndrome-disease-drug-quantity" of Fu Qing-zhu Nvke,it is found that they are connected with each other through treatment,and the medicinal characteristics and theoretical connotation of the drugs used also confirm this relationship.Therefore,this study refined and summarizes the treatment characteristics and medication characteristics involved in it,and draws the following conclusions.Treatment characteristics:According to the characteristics of modern gynecological diseases involved in Fu Qing-zhu Nvke,it is concluded that:①liver blood to relieve liver and abdominal pain and collapse,the representative party is Xuanyi meridian soup and liver blood to relieve depression for menstruation,the representative party is calm soup;heart and spleen liver and kidney to relieve depression for treatment of amenorrhea,the representative of Fang Yijing soup.The understanding of"depression" includes "yu" whether can change "fire" and different treatment rules of the weight of "fire",if only replenish the blood and calm the liver;if the heavy need to replenish the liver+qi;if depression and fire,fire is light,need to replenish the liver+clear heat and relieve fire;if the fire is heavy,need to replenish blood and liver+qi+nourish Yin and relieve fire.②Fill essence qi to cure the collapse,representing the prescription of sperm hemostasis soup.③Fill temper to cure the trouble,fetal unrest,abortion,on behalf of the gas soup.④Supplement liver blood to remove phlegm wet treatment red belt,pregnancy evil,on behalf of the liver stop soup,eliminate evil an fetal soup.⑤Blood to treat postpartum abdominal pain,on behalf of the square powder knot fixed pain soup.⑥To treat infertility with hernia removal,representing Fang Sheng with soup.Drug characteristics:the syndrome of Fu Qing-zhu Nvke,blood syndrome,qi deficiency syndrome,qi depression syndrome,fine deficiency syndrome and Yin deficiency syndrome are more related to spleen and kidney,and depression syndrome is more related to liver and spleen.And Fu Qing-zhu Nvke to the overall concept for the use,with the five elements theory of the pathogenesis,kidney water and lung gold for the mother and child relationship,kidney water and heart fire,water and fire;the liver and spleen and soil restrict each other,soil congestion.Its medication is sweet and bitter,Gan can healthy temper,yixin Yang,with bitter taste can dry wet,reduce lung qi,nourishing Yin and clean profit.Warm can help Gan warm Yang spleen clearing damp,help bitter warm cold water.It is in line with the pathogenesis,care for the whole,all the dirty,and can accurately select drugs,play the curative effect.Conclusions:1.It is found that the determination of the disease syndrome in Fu Qing-zhu Nvke is based on the theories of zang-fu organs,essence,qi,blood and body fluid,strange classics and five elements theory,which reflects the "quantitative thinking" in the theory of viscera syndrome.2.In this study,the treatment characteristics of Fu Qing-zhu Nvke are the treatment characteristics of supplementing the heart,spleen and liver,relieving the blood and relieving the blood,removing the phlegm by removing the liver and blood,and removing the temper,and removing the blood and removing the blood stasis.3.Drug is mainly warm,often use sweet and sorrows.Gan can healthy temper,heart Yang,bitter can dry wet,lung qi,nourishing Yin clean.Warm can help Gan warm Yang spleen clearing damp,help bitter warm cold water.