Cross-sectional Study Of Diabetic Kidney Disease In Urban And Suburban Areas Of Chongqing’s Main Districts

ObjectiveTo investigate the prevalence of diabetic kidney disease(DKD)among the patients with type 2 diabetes mellitus in Chongqing’s main districts.To compare the differences of prevalence and correlation factors of DKD between urban and suburban areas.MethodsFrom March 2019 to July 2019,a total of 735 patients with type 2 diabetes mellitus in Chongqing’s main districts were selected by stratified cluster random sampling,of which 434 patients were from urban communities and 301 patients from suburban communities.Differences in demographic characteristics,physical measurement,metabolic indicators,fundoscopy,carotid ultrasound,comprehensive control rate of diabetes and prevalence of DKD were analyzed.Multivariate Logistic regression model was used to analyze the correlation factors of DKD.Results1.The overall prevalence of DKD in type 2 diabetic patients of Chongqing’s main districts was 31.3%,and the prevalence of patients in suburbs(35.9%)was higher than that in urban areas(28.1%,P<0.01).2.Systolic blood pressure(SBP),diastolic blood pressure(DBP),waist-to-hip ratio,fasting blood glucose(FBG),hemoglobin A1c(HbA1c),and urine albumin(UAlb),triglycerides(TG),total cholesterol(TC)and high density lipoprotein(HDL)of suburban patients were significantly higher than that of urban patients(P<0.05).However,age,educational level,monthly income,urinary creatinine,uric acid and the prevalence of carotid plaque of suburban patients were significantly lower than that of urban patients(P<0.05).3.In terms of blood sugar control,the FBG and HbA1 c control rates in urban patients were 40.6% and 44.2%,respectively,which were significantly better than those in suburban patients(27.9%,32.2%,P<0.01,P<0.01).But there were no gender differences in blood sugar control(P>0.05).In terms of blood lipid control,the TG control rate in urban patients was 61.5%,which was better than that in suburban patients(49.2%,P<0.05).But there were no significant differences in TC,HDL and low density lipoprotein(LDL)control between the urban and suburban patients(P>0.05).The control rates of TC and HDL in men were 35.2%and 92.7%,respectively,which were better than those in women(22.5%,82.7%,P<0.001,P<0.01).There were no gender differences in other indicators(P>0.05).In terms of blood pressure control,the blood pressure control rate in urban patients was 59.9%,which was significantly better than that in suburban patients(37.2%,P<0.01).But there were no significant differences between genders in blood pressure control(P>0.05).In terms of body mass index(BMI)control,there were not urban-suburban differences or gender differences in BMI control(P>0.05).4.Multivariate Logistic regression analysis showed that the correlation factors of DKD in all patients of Chongqing’s main districts were age(OR=1.669,95%CI 1.178-2.364,P=0.004),SBP(OR=2.416,95%CI 1.705-3.424,P<0.001),diabetes duration(OR=1.757,95%CI1.240-2.489,P=0.002),HbA1c(OR=2.277,95%CI 1.567-3.309,P<0.001),TG(OR=1.740,95%CI 1.228-2.467,P=0.002)and uric acid(OR=1.980,95%CI 1.347-2.909,P=0.001),while tensin-converting enzyme inhibitor(ACEI)or angiotensin receptor blocker(ARB)(OR=0.358,95%CI 0.199-0.642,P=0.001)and TC(OR=0.647,95%CI 0.436-0.960,P=0.030)were negatively correlated with DKD.There are differences in the correlation factors of DKD between urban and suburban areas,gender and age.ConclusionThe prevalence of DKD in patients with type 2 diabetes in Chongqing’s main districts was31.3%,and the prevalence of DKD in suburban patients(35.9%)was significantly higher than that in urban patients(28.1%).Factors such as age,SBP,course of disease,HbA1 c,TG,uric acid,ACEI or ARB drugs were significantly associated with DKD.There are differences in the correlation factors of DKD between urban and suburban areas,gender and age.