| Objective: Because the pathogenesis of category Ⅲ prostatitis,namely chronic prostatitis/chronic pelvic pain syndrome,is complex and unclear,so that its diagnosis and treatment measures have not achieved good results.By analyzing the relationship between the changes of calcium concentration in expressed prostatic secretion and serum and the occurrence and development of the disease,we hope to provide a new basis for the clinical diagnosis of type Ⅲ chronic prostatitis.Methods: The subjects of the study were patients with category Ⅲ prostatitis patients who participated in physical examination in Guilin,Guangxi,China and normal healthy men in the control group.After EPS and serum samples were collected,the calcium ion concentration of the samples were determined separately by a flame atomic absorption spectrometer(BH7100S)equipped with a calcium hollow cathode lamp(422.7nm)and statistical analysis were performed by softwares of SPSS 28.0 and Medcalc.Results: The study included 45 healthy controls and 84 patients with category Ⅲ prostatitis,including 42 cases of category Ⅲa and 42 cases of category Ⅲb.Compared with healthy controls,calcium ion concentrations of EPS and serum were significantly lower in patients with category Ⅲ prostatitis(P<0.05),there was no correlation in calcium ion concentration neither in category Ⅲ prostatitis group(Ⅲa/Ⅲb/Ⅲa+b)nor in healthy control group,and the AUC values of calcium ion concentration in different groups were all above 0.8.The sensitivity of serum calcium concentration in patients with category Ⅲa prostatitis was88.10%.Conclusions: Calcium concentration of EPS and serum play an important role in category Ⅲ prostatitis,which may have potential diagnostic value and may help predict category Ⅲa/Ⅲb prostatitis. |
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