| Purpose: In this thesis,the clinical information of patients with osteoporosis(OP)was collected,and the TCM syndrome elements diagnosis was calculated by referring to the scale of syndrome differentiation.The distribution law of disease location and syndrome elements was analyzed,and the difference of syndrome elements distribution in different groups was explored,aiming to provide theoretical basis for the diagnosis of TCM syndrome elements in OP patients.Improve the accuracy and standardization of syndrome differentiation,and provide more reasonable TCM diagnosis and treatment methods for OP patients of different groups.Methods: OP patients who met the requirements were collected according to the criteria,their basic information and the information of TCM four diagnosis were sorted out,and the input data were sorted and classified by Excel.According to the diagnosis method in Syndrome Differentiation,the syndrome elements were identified,and the gender,age and Body Mass Index(BMI)of 270 subjects were grouped according to the relevant classification standards,and then the disease location and distribution rule of the syndrome elements were described.To study the difference of occurrence rate and severity of syndrome elements among different groups.SPSS 25.0 was used for statistical analysis in this study.Results:1.General information: Among the 270 subjects,there were 52 male patients,accounting for 19.3%,and 221 female patients,accounting for 80.7%,with a male/female ratio of1:4.2.In the age group,59 patients were in the non-elderly group,accounting for 21.9%,and221 patients were in the elderly group,accounting for 78.1%.In the BMI group,there were14 patients with underweight(5.2%),134 patients with normal weight(49.6%),90 patients with overweight(33.3%),and 32 patients with obesity(11.9%).2.Distribution rule of overall syndromes in OP patients: there were 17 disease location syndromes and 21 disease syndromes according to statistics.The frequency ≥ 50% was defined as the constant witness.In this study,four common syndromes were found: kidney,liver,spleen and bones;Six common syndromes were obtained: Yin deficiency,Yang deficiency,qi deficiency,blood deficiency,qi stagnation and blood stasis.3.Distribution rule of syndrome elements grouped by gender: in the male group,there were 13 syndrome elements,including 5 common witness elements,namely kidney,muscles and bones,liver,meridians and spleen.There were 19 syndromes,of which 5 were common syndromes,namely Yin deficiency,qi deficiency,dampness,blood deficiency and Yang deficiency.In the female group,there were 17 syndromes,among which there were 4common syndromes,namely kidney,liver,spleen and bones.The results showed that there were 20 syndromes,among which there were 4 common syndromes,which were Yin deficiency,Yang deficiency,qi deficiency and blood deficiency.There were significant differences in the occurrence rates of 11 syndrome elements in this group(P < 0.05).The occurrence rate of syndrome in male group was higher than that in female group,which included muscles and bones,meridians,lung,mind,dampness,Yang hyperactivity,jing deficiency,dynamic wind and external wind,while that in female group was higher than that in male group,which included Yang deficiency and qi stagnation.In addition,the severity of5 syndrome elements in this group had statistical difference(P < 0.05).The symptoms of lung,skin and dampness were more severe in male group than female group.The syndrome elements of Yin deficiency and moving wind were higher in female group than in male group.4.Distribution rule of syndrome elements in age group: there were 14 syndromes in non-elderly group,among which 3 were common witnesses,namely spleen,liver and kidney;There were 20 syndromes,among which 3 were common syndromes,which were Yang deficiency,Yin deficiency and qi deficiency.There were 17 syndromes in the elderly group,among which 4 were common syndromes,namely kidney,liver,muscles and bones,and spleen.There were 18 syndromes,among which 3 were common syndromes,namely Yin deficiency,Yang deficiency,blood deficiency,qi stagnation and blood stasis.There were significant differences in the occurrence rates of 8 syndrome elements in this group(P <0.05).The occurrence rate of syndromes in stomach and small intestine in non-elderly group was higher than that in elderly group.The syndrome factors of kidney,muscles and bones,Yin deficiency,blood stasis,jing deficiency and external wind were higher in the elderly group than in the non-elderly group.In addition,the severity of 5 syndrome elements in this group had statistical difference(P < 0.05).The severity of syndromes in the non-elderly group was higher than that in the elderly group,and the syndromes in the elderly group were higher than that in the non-elderly group,including deficiency of stomach,heart,gallbladder and essence.5.Distribution rule of syndrome elements in BMI grouping: in the underweight group,there were 9 syndrome elements,including 3 common witness elements,which were kidney,muscles and bones,and spleen;There were 13 syndromes,including 5 common witness elements,which were Yin deficiency,qi deficiency,Yang deficiency,blood deficiency and blood stasis.There were 9 syndromes in the normal weight group,among which 3 were common syndromes,namely kidney,muscle and spleen.There were 13 syndromes and 5common witness elements,which were Yin deficiency,Qi deficiency,Yang deficiency,blood deficiency and blood stasis.There were 14 syndromes obtained by super-recombination,including 4 common witness elements,which were kidney,liver,spleen and bones.14 syndromes were obtained,including 6 common witness elements,which were Yin deficiency,Yang deficiency,qi deficiency,blood deficiency,blood stasis and qi stagnation.In the obese group,there were 14 syndromes,including 4 common witness elements,which were kidney,liver,spleen and bones.There were 14 syndromes,and 5 common syndromes,which were Yin deficiency,Yang deficiency,qi deficiency,dampness and blood deficiency.There were statistical differences in the occurrence rates of 5 syndrome elements in the group(P < 0.05).The occurrence rates of syndrome elements in lung and mind were higher in the underweight group than in other groups.The occurrence rate of syndrome element dampness,cold and blood cold was higher in obesity group than other groups.In addition,there were two syndrome elements in this group with statistical difference in severity(P < 0.05).The severity of syndrome dampness and hyperyang was higher in obesity group than in other groups.6.Director Zhang Liyun’s diagnosis and treatment experience: Concluded that the primary pathogenesis of this disease is this deficiency syndrome,which is based on kidney deficiency,but related to the disease location of spleen,liver and other viscera.From the point of view of disease,it is closely related to the imbalance of Yin and Yang,the disorder of qi and blood,qi stagnation and blood stasis.After years of clinical diagnosis and treatment,we have summed up the empirical prescription,which focuses on tonifying the kidney,taking into account other zang-fu organs,harmonizing Yin and Yang,qi and blood in order to calm down.If there is evidence,medication will be adjusted according to symptoms and pathogenesis.This method is clear in syndrome differentiation,giving consideration to specimens,flexible in medication and good therapeutic effect.Conclusion:1.The disease site of OP is mainly kidney,which is related to spleen and liver.The symptoms are mainly muscles,bones and meridians,suggesting that attention should be paid to regulating kidney,spleen and liver as well as strengthening muscles and bones and thinning meridians in clinical treatment.2.The disease of OP is mainly characterized by deficiency syndrome,including Yin deficiency,Yang deficiency,qi deficiency and blood deficiency,etc.Solid syndrome element mostly sees qi stagnation,blood stasis and phlegm dampness.3.The number of female patients was significantly more than that of male.The occurrence rate of syndrome elements of muscles and bones,meridians,lung,mind,dampness,hyperyang,sperm deficit,dynamic wind and external wind was higher in male group than in female group.The occurrence rate of syndrome Yang deficiency and qi stagnation in female group was higher than that in male group.4.The number of patients in the elderly was significantly higher than that in the non-elderly patients,and the occurrence rate of syndrome stomach and small intestine was higher in the non-elderly group than in the elderly group.The incidence of syndrome of kidney,muscles and bones,Yin deficiency,blood stasis,sperm deficiency and external wind was higher in the elderly group than in the non-elderly group.Therefore,in the clinical diagnosis and treatment of middle-aged and elderly patients should pay attention to supplement deficiency,and early prevention and screening for the prevention and treatment of OP is also important.5.In the BMI group,the incidence of syndrome hormone lung and mind was higher in the underweight group than in other groups;The occurrence rate of syndrome element dampness,cold and blood cold was higher in obesity group than other groups.The severity of syndrome dampness and hyperyang was higher in obesity group than in other groups.6.Zhang Liyun chief physician on the basis of many years of experience in treatment of OP,summarized the primary pathogenesis is the deficiency of the disease,treatment of kidney empty follow theory,liver and spleen,qi and blood,Yin and Yang whole regulation,give attention to two or morethings severely,using empirical and subtract medicine syndrome differentiation,knowledge is often change,treatment effect is good,the diagnosis and treatment experience is worth learning and research. |
PDF Full Text Request