Clinical Observation Of Wuling Wendan Decoction In The Treatment Of Infantile Enuresis(Spleen Deficiency And Phlegm Accumulation)

Objective:In this study,through the clinical observation of Wuling Wendan decoction in the treatment of infantile enuresis(spleen deficiency and phlegm accumulation type),the clinical curative effect and the integral changes of primary and secondary symptoms were counted and analyzed.to observe the clinical efficacy of Wuling Wendan decoction in the treatment of infantile enuresis(spleen deficiency and phlegm accumulation type),which provides a new idea for the treatment of infantile enuresis with traditional Chinese medicine.Methods:72 children who met the inclusion criteria in the pediatric clinic of the second affiliated Hospital of Heilongjiang University of traditional Chinese Medicine were randomly divided into two groups with 36 children in each group(n = 36).The experimental group was given Wuling Wendan decoction orally,and the control group was given Xingpi Yanger granule orally.Both groups were treated for 4 weeks.The total effective rate of the two groups after 4 weeks of treatment,and the changes of syndrome scores of primary and secondary symptoms before and after treatment were observed and statistically analyzed.The non-ineffective cases were followed up 3 months after drug withdrawal,and the recurrence rate was calculated.Results:1.General comparison: Chi-square test showed that there was no significant difference in age,sex and course of disease between the two groups(P > 0.05).2.Overall efficacy analysis: comparing the total effective rate of the two groups,the total effective rate of the test group was 94.29%,which was higher than that of the control group(71.43%),and the difference was statistically significant(P < 0.05),indicating that the clinical effect of the experimental group was better than that of the control group.3.Comparison within the group: there were significant differences in the main symptoms(enuresis times,sleep depth),secondary symptoms(fatigue,poor appetite,thin stool,sputum between the throat)and the total score of TCM syndrome between the two groups before and after treatment(P < 0.05).The results showed that the treatment methods of the two groups could improve the symptoms of the disease.4.Comparison between groups: after 4 weeks of treatment,the total scores of main symptoms,secondary symptoms,individual syndromes and TCM syndromes were compared between the experimental group and the control group,and there was significant difference between the two groups(P < 0.05).That is,the total scores of primary and secondary symptoms,single syndrome and TCM syndrome were improved in the two groups,and the experimental group was better than the control group.5.Recurrence analysis: there were 2 cases of recurrence in the test group and 9 cases in the control group,the difference was statistically significant(P <0.05),indicating that the recurrence rate in the test group was lower than that in the control group.Conclusion:1.Wuling Wendan decoction is effective in the treatment of infantile enuresis(spleen deficiency and phlegm accumulation type),and it is better than Xingpi Yanger granule.2.Wuling Wendan decoction is superior to Xingpi Yanger granule in improving the main symptoms(frequency of enuresis,sleep depth)and secondary symptoms(fatigue,poor anorexia,thin stool,sputum between throat).3.Wuling Wendan decoction is superior to Xingpi Yanger granule in reducing the recurrence rate of infantile enuresis(spleen deficiency and phlegm accumulation type).