Efficacy Of Qinggan Powder Combined With Lecardipine In The Treatment Of Primary Hypertension With Hyperactivity Of Liver Yang

Research purposes: The purpose of this study is to observe the clinical efficacy of Qinggan SAN and point application on hypertension patients with hyperactivity of liver Yang through a randomized controlled trial.Methods: Methods: 80 patients meeting inclusion criteria were randomly divided into experimental group and control group(40 cases in each group).Treatment plan: Control group was health education and oral lecardipine tablet,10mg/ time,once a day;Group is based,qinggan scattered in the control group(rhizoma coptidis,evodia rutaecarpa)were applied in bilateral yongquan point and lr 3 point,course of treatment for 14 days,before and after treatment respectively 24 h ambulatory blood pressure in patients with evaluation and TCM syndrome integral,during the period of treatment,the daily monitoring of the patient’s blood pressure,using SPSS20.0 software for data statistics and analysis,The changes before and after and between the two groups were compared.Results:1.Before treatment,there were no significant differences in general data,blood pressure values,24 h ambp and TCM syndrome scores between the experimental group and the control group(P>0.05),indicating that the two groups were comparable.2.After treatment,the blood pressure values and 24 h dynamic blood pressure of the two groups before and after treatment decreased significantly compared with that before treatment,with statistical significance(P < 0.05),indicating that both groups had good antihypertensive effect.3.After treatment,the blood pressure compliance rates of the experimental group and the control group were 94.7% and 76.8%,respectively,and there was a statistical difference in the efficacy between the groups(P < 0.05).The blood pressure and 24-hour dynamic blood pressure of the experimental group were lower than those of the control group,with statistical significance(P < 0.05),indicating that the hypotensive effect of the experimental group was better than that of the control group.4.After treatment,the total score and single score of syndrome in both groups decreased significantly compared with before treatment(P < 0.05),indicating that the treatment plan can effectively improve symptoms in both groups.5.After treatment,the TCM syndrome integral effective rate of experimental group and control group was 94.70% and 72.80%,respectively,with statistical difference between groups(P < 0.05);And compared with the control group,there were statistical differences in the total score of TCM syndrome,dizziness,headache,eye red,bitter mouth and insomnia in the experimental group(P < 0.05).The results showed that the experimental group was better than the control group in improving TCM syndrome,especially in dizziness,headache,eye red,bitter mouth and insomnia.Conclusion: Compared with the control group,qinggan Powder combined with lecardipine for the treatment of primary hypertension with hyperactivity of liver Yang,its antihypertensive effect was significant,and the TCM syndrome of patients was improved well.