| Objective:Through the observation of the efficacy and safety of Zhuang medicine whole body medicine bath therapy in the treatment of psoriasis vulgaris(blood stasis syndrome),this paper analyzes the characteristics and advantages of this therapy,so as to lay a clinical foundation for ethnic medicine in the treatment of psoriasis vulgaris(blood stasis syndrome).Methods:70 patients with psoriasis vulgaris(blood stasis syndrome)who met the inclusion criteria were randomly divided into two groups,with 35 cases in each group.Treatment group: Zhuang medicine whole body medicine bath therapy + NB-UVB phototherapy + compound Flumetasone cream + white vaseline;Control group: NB-UVB phototherapy + compound Flumetasone cream + white vaseline.The course of treatment of both groups was 8 weeks.The changes before and after treatment were evaluated by PASI score,DLQI score,traditional Chinese medicine symptom score,dermoscopy score and the incidence of adverse reactions.The clinical efficacy of Zhuang medicine whole-body medicine bath therapy was discussed by statistical analysis and comparison of the data before and after treatment.The effective number was followed up 3 months after the end of treatment,and the recurrence rate was observed.Results:A total of 70 cases were included.One case fell off in the treatment group,and 69 cases were finally treated.There were 34 cases in the treatment group and 35 cases in the control group.There was no difference in gender,age,course of disease and treatment history between the two groups(P > 0.05).There was no significant difference in PASI score,DLQI score,dermoscopy score and TCM syndrome score between the two groups before treatment(P > 0.05).After treatment:(1)PASI score:(1)After 4 weeks of treatment,the score of the treatment group was(15.92 ± 4.95)before treatment and(10.26 ± 3.73)after treatment;The score of the control group was(16.40 ± 5.41)before treatment and(12.19 ± 4.36)after treatment.The PASI score of the two groups did not improve significantly(P > 0.05).(2)After 8 weeks of treatment,the PASI scores of the treatment group and the control group were(4.01 ± 2.24)and(6.60 ± 2.50)respectively.The difference between the two groups was statistically significant(P < 0.05),and the improvement in the treatment group was more obvious than that in the control group(P < 0.05).(2)DLQI score: the score of the treatment group was(10.55 ± 2.12)before treatment and(4.14 ± 0.78)after treatment;The control group was(10.02 ± 2.38)points before treatment and(5.94 ± 1.71)points after treatment.The difference between the two groups was statistically significant(P < 0.05).The improvement in the treatment group was more obvious than that in the control group(P < 0.05).(3)Dermatoscope score: in the treatment group was(8.23 ± 1.72)before treatment and(2.73 ± 1.42)after treatment;The control group was(8.20 ± 1.51)points before treatment and(3.34 ± 1.10)points after treatment.The difference between the two groups was statistically significant(P < 0.05).The improvement in the treatment group was more obvious than that in the control group(P < 0.05).(4)TCM symptom score: the score of the treatment group was(8.29 ± 1.62)before treatment and(4.88 ±1.09)after treatment;The control group was(8.40 ± 1.59)before treatment and(6.31 ± 1.64)after treatment.The difference between the two groups was statistically significant(P < 0.05).The improvement in the treatment group was more obvious than that in the control group(P < 0.05).(5)The total effective rates of the treatment group and the control group were 82.35% and 68.57%respectively.The difference between the two groups was statistically significant(P < 0.05).(6)Safety: there were 2 cases of adverse reactions in the treatment group,and the incidence of adverse reactions was 5.88%;There were3 cases of adverse reactions in the control group,and the incidence of adverse reactions was 8.57%.There was no significant difference between the two groups(P > 0.05).(7)Recurrence rate: the effective number was followed up3 months after the end of treatment.There were 3 cases of recurrence in the treatment group,and the recurrence rate was 10.71%;There were 10 cases of recurrence in the control group,and the recurrence rate was 41.67%.The recurrence rate in the treatment group was significantly lower than that in the control group(P < 0.05).Conclusion:(1)Zhuang medicine bath therapy can improve the clinical efficacy of psoriasis vulgaris(blood stasis syndrome).The total effective rate of the treatment group is higher than that of the control group.Among them,the number of cured and effective people in the treatment group is significantly higher than that in the control group,and the quality of life is also better than that in the control group;(2)Compared with the control group,the safety of Zhuang medicine bath therapy has no significant difference,but the recurrence rate is significantly lower than that of the control group.It is suitable for clinical promotion.It is a safe and effective characteristic therapy of Zhuang medicine. |
PDF Full Text Request