Objective:By sorting out the case data of elderly patients with coronary heart disease,the distribution characteristics of syndrome types of elderly coronary heart disease were discussed,and the application rules of Traditional Chinese medicine were discussed by using data mining technology.Methods:Data of 290 cases that met the inclusion criteria from July 2019 to June 2021 were collected,and standardized data processing was performed on the collected data.Micrisift Office Excel 2007 software was used to establish electronic data,and chi-square test and rank-sum test were used for statistical analysis.The test result<0.05 was statistically significant.SPSS 25.0 was used for frequency and cluster analysis of TCM,and SPSS Modeler 18.0 was used for correlation analysis of TCM.Results:1.Among 290 CHD patients included in the study,136 were male,accounting for 47%,and 154 were female,accounting for 53%.Female:male=1.13:1.The seasonal incidence rates were 31.72%in spring,38.62%in winter,10.34%in summer and 19.32%in autumn,respectively.The onset of spring,light snow,light cold,winter solstice,rain and light snow are the first six solar terms.2.The TCM syndrome type distribution of the 290 elderly patients with CHD was as follows:96 cases of qi deficiency and blood stasis syndrome,accounting for 33.10%;75 cases of deficiency of qi and Yin and blood stasis syndrome accounted for 25.86%;49 cases of qi stagnation and blood stasis syndrome,accounting for 16.90%;37 cases(12.76%)were heat-toxic and blood-stasis syndrome.14 cases of phlegm blocking blood stasis syndrome,accounting for 4.83%;13 cases of cold coagulation and blood stasis syndrome(4.48%);6 cases,accounting for 2.07%.Among them,qi deficiency and blood stasis syndrome,qi and Yin deficiency,blood stasis and qi stagnation and blood stasis syndrome accounted for 58.96%of all cases.3.204 prescriptions of traditional Chinese medicine for treating elderly coronary heart disease were collected this time,which were divided into 18 kinds of drugs and totaled 118 kinds of traditional Chinese medicine.Among them,tonifying drugs,promoting blood circulation and removing blood stasis drugs and regulating qi drugs are used frequently.There were 54 commonly used drugs in the treatment of coronary heart disease angina pectoris,and the top 10 drugs in frequency were salvia miltiorrhiza,ligusticum chuanxiong,radix paeoniae root,Astragalus membranaceus,Angelica,Poria cocos,Codonopsis pilosula,safflower,Panax notoginseng and Atractylodes macrocephala.4.Cluster analysis results:C1 included 12 traditional Chinese medicines including keel,Oyster,polygala,radix paeoniae root,Codonopsis pilosula,Radix Ophiopogonis,Fructus schisandrae,Atractylodes atractylodis,Astragalus membranaceus,Poria cocos,Cypress seed and ligusticum chuanxiong.C2 includes safflower,peach kernel,Angelica and Panax notoginseng;C3 includes bupleurum,Rhizome,jujube seed,chicken gold and malt.C4 includes 7 herbs including Trichosanthes trichosanthes,Fructus aurantii,Allium macrostemon,Corydalis corydalis,cinnamomum twig,Fructus aconite and Fructus fructus fructus.C5 includes orange peel,pinellia ternata,salvia miltiorrhiza and Anemone.5.Results of association analysis:32 high-frequency Chinese medicines were analyzed by association analysis(set support level at 15%and confidence level at 95%),and the drugs were ranked in descending order according to confidence level.When the preceding item is set to 1,there will be Hypotension and salvia miltiorrhiza.Aurantium trifoliate,Salvia miltiorrhiza;Fructus trichosanthes,Salvia miltiorrhiza;Allium macrostemon,Salvia miltiorrhiza;Keel,oyster and other 16 drug pairs combination.When the maximum preceding term is set to 2,there will be Hypotension,salvia miltiorrhiza and Ligusticum chuanxiong.Fructus aurantii,Fructus trichosanthes,Salvia miltiorrhiza;Aurantium,Allium macrostemon,Salvia miltiorrhiza;Fructus trichosanthes,Allium macrostemon,salvia miltiorrhiza;20 drug groups such as polygala,radix paeoniae,Ligusticum chuanxiong etc.Conclusion:1.According to the data mining method,the syndrome type distribution of elderly coronary heart disease patients is mainly qi deficiency and blood stasis syndrome,qi and Yin deficiency syndrome and blood stasis syndrome,which is consistent with the pathological characteristics of elderly coronary heart disease based on qi and Yin deficiency,phlegm,turbidness and blood stasis,which is basically consistent with modern clinical studies.2.Through drug clustering and association analysis on medication of elderly patients with coronary heart disease,drug pairs and drug groups of high-frequency drugs were obtained,and the medication law of TCM treatment of the disease was discussed,which could provide a more intuitive reference for clinical medication and literature research. |