Clinical Observation On The Treatment Of Early Threatened Abortion With Uterine Effusion With Kidney Deficiency And Blood Stasis By Bushen Huayu Zhixue Prescription And Analysis Of Factors Related To The Outcome Of Fetal Stability

Objective : 1.By observing clinical observation of Bushen Huayu Zhixue prescription in treating early threatened abortion with uterine effusion,it provides a reference for the clinical treatment.2.Through a retrospective study,the factors influencing the outcome of fetal stability of early threatened abortion with uterine effusion were discussed,providing data support for early clinical monitoring of high-risk patients and intervention of high-risk factors.Methods : 1.65 patients who up to standard were randomly divided into experimental group and control group.The control group was cured with basic treatment + progesterone injection,and the experimental group was cured with basic treatment + progesterone injection+ Bushen Huayu Zhixue prescription on the basis of the control group.Serum β-human chorionic gonadotropin(β-HCG),estradiol(E2),progesterone(P),TCM syndrome score,and the changes of uterine effusion of 2 groups were recorded before and 14 days after treatment.2.We collected data of patients by retrospective study method,according to the outcome of fetal stability,grouping 84 cases into successful group,18 cases into failed group.Excel was used to all record effective data and SPSS statistical software was used for statistical analysis.Results:1.There were statistical differences in serum β-HCG,E2 and P between the experimental group and the control group before and after treatment(P < 0.05).There were statistical differences in the area of uterine effusion and TCM syndrome score in the experimental group before and after treatment(P<0.05);After treatment,there were stastistically significant differences in serum β-h CG,P,E2 value,the area of uterine effusion,TCM syndrome score,the efficacy of TCM syndromes and comprehensive curative effect between the two groups(P<0.05).2.There was no statistical differences in age,numbers of previous pregnancies,numbers of previous abortion between the successful group and the failed group(P>0.05).There were stastistically significant differences in the number of previous intrauterine operations,dream intercourse during pregnancy,abdominal painplasma and D-dimer between the two groups(P<0.05).At 5,6 and 7 weeks of gestation,the serum E2 level in the successful group was higher than that in the failed group(P<0.05),and the level of blood P and β-HCG at 6 to 7 weeks of pregnancy were higher than that in the failed group(P<0.05).Conclusions:1.Bushen Huayu Zhixue prescription can effectively treat early threatened abortion complicated with uterine effusion,reduce the area of effusion,improve clinical symptoms and improve the success rate of fetal preservation.2.Dream intercourse during pregnancy,abdominal pain,previous intrauterine operation and plasma D-dimer level are the important factors leading to the failure of outcome of fetal stability in patients with early threatened abortion complicated with uterine effusion.