Study On The Relationship Between Legume Food Intake And Hyperuricemia In Community Adult Residents In Luzhou

Objective: To understand the prevalence and influencing factors of legume food intake and HUA among adult community dwellers in Luzhou,to analyze the relationship between legume food intake and HUA among adult community dwellers in Luzhou,and to provide a scientific basis for dietary guidance for HUA patients.Methods: According to a multi-stage stratified random sampling method,the food frequency method questionnaire was used to survey the intake of legumes among adult community residents in Luzhou City from November 2020 to June2021 in three districts and four counties of Luzhou City through a face-to-face survey,and physical and biochemical examination indicators were collected using the Sichuan Provincial Basic Public Health Service database.SPSS.25 software was used to do data analysis and processing.After matching the confounding factors of the two groups according to 1:2 using the nearest neighbor propensity score to equalize,logistic regression model was used to analyze the correlation between legumes and HUA before and after matching,and factor analysis was used to establish a legumes food dietary model and analyze the characteristics of legumes food dietary pattern and logistic regression analysis model to analyse the relationship between dietary patterns of legumes and HUA.Results:(1)A total of 1,692 cases were sampled for the survey,and a total of1,536 cases were eventually included.The average uric acid level of the population was 309.43±94.75μmol/L.Among them,195 cases suffered from HUA,with a detection rate of 12.7%,23.3% and 4.8% for men and women respectively.(2)The proportion of men,smoking and alcohol consumption in the HUA group was higher than that in the non-HUA group.The education level and per capita monthly income in the HUA group were higher than those in the non-HUA group,and the detection rates of hypertension,dyslipidemia,obesity and central obesity in the HUA group were higher than those in the non-HUA group,with statistically significant differences.(3)The legume food intake of adult residents in Luzhou community was13.26g/d,11.23g/d in the HUA group and 13.58g/d in the non-HUA group,and the difference between the two groups was statistically significant.(4)The pre-matching results showed that intake of Q4 group(≥28.85g/d)was negatively associated with the risk of HUA prevalence(OR=0.57 95% CI:0.28～0.79)compared to the Q1 group(0～6.19g/d)of total legumes for adult residents in the Luzhou community.Results after propensity score matching showed no association between total legume food intake and HUA prevalence(OR=0.60 95% CI: 0.34～1.07).Analysis of the relationship between legumes and HUA stratified by whether the legumes were processed or not showed no significant association between unprocessed legumes and fermented legumes and HUA prevalence(P>0.05),and a negative association between intake of non-fermented legumes and risk of HUA prevalence(OR=0.34 95% CI:0.18～0.63).Factor analysis yielded three legume food patterns,namely soybean and non-fermented soybean products pattern,fermented soybean products pattern and miscellaneous soybean/curd pattern.After adjusting for confounding factors,the results showed that the soybean/curd pattern was positively associated with HUA prevalence,while the soybean and non-fermented soybean products pattern and fermented soybean products pattern were not significantly associated with HUA prevalence.Conclusions: The adult population in the Luzhou community consumed less than the recommended intake of legumes.Total legume food intake was not statistically associated with HUA,but the intake of non-fermented legume products was negatively associated with HUA prevalence.