Efficacy Of Biodentine Used For Pulpotomy In Primary Molars With Carious Pulp Exposure: A Meta-analysis

ObjectiveTo provide evidence for dental practice by assessing the effectiveness of Biodentine with those of other pulpotomy techniques in primary molars.MethodsPub Med,Cochrane,Embase,Web of Science,Google Scholar,CNKI,Wanfang Database and VIP Database were searched in conjunction with hand searching.Study selection,data extraction and study appraisal were performed independently by two authors.A consensus was reached through discussion with a third reviewer when disagreements arose.All analyses were performed using Review Manager 5.3.ResultsA total of 576 articles were initially identified.Based on the inclusion and exclusion criteria,the final analysis included 16 articles.As for the clinical success rates of Biodentine vs MTA,Comparison of the efficacy by risk ratio(RR)did not indicate any significant difference between Biodentine and MTA in clinical success at follow-up of 6 months(RR=1.01;95%CI:0.98-1.03),12months(RR=0.99;95%CI:0.96-1.02),18 months(RR=0.99;95%CI:0.94-1.04)and 24 months(RR=0.97;95%CI:0.91-1.04).A similar result was found between Biodentine and MTA in radiographic success at follow-up of 6 months(RR=0.99;95% CI:0.96-1.01),12 months(RR=0.96;95%CI:0.93-1.00),18months(RR=1.00;95%CI:0.93-1.06)and 24 months(RR=0.97;95%CI:0.90-1.03).ConclusionCurrent evidence showed that,the efficacy of Biodentine is significantly similar to MTA.The results suggest Biodentine is likely as a potential pulp-capping medicament.