| Objectives:Among the top seven causes of cancer-related death,common gastrointestinal tract cancers are major contributors including colon and rectum cancer,stomach cancer,liver cancer,pancreatic cancer,and esophageal cancer.Gastrointestinal tract cancers not only damages people’s health,but also caused economic burden.Data on global and country-specific levels and trends of common cancers of the gastrointestinal tract are essential to understand the impact of these diseases and to help policymakers to allocate resources.Methods:Cancer mortality,and incidence were obtained from Global Burden of Disease Study 2019,according to regions,sex and social demographic index(SDI)level,the data were sorted out.Age-standardized incidence rate and death rate of common gastrointestinal tract cancers were performed by region,sex and SDI,as well as change rate.Results:In 2019,there was an age-standardized incidence rate of 61.9(95%CI 56.167.6)per 100 000 person-years in terms of five major cancers of the gastrointestinal tract.Globally,there was a decrease in age-standardized incidence rates in stomach cancer,esophageal cancer and liver cancer from 1990 to 2019;and there was a decrease in age-standardized death rates in four tumors,except for pancreatic cancer.Stratified using SDI,the high SDI,and high-middle SDI locations recorded the highest incidence rate and death rate of colon and rectum cancer and pancreatic cancer,whereas the low-middle SDI,and low SDI locations possessed the highestburden of stomach cancer and esophageal cancer.Overall,the incidence rate and death rate of five major cancers of the gastrointestinal tract in men were higher than that in women.Conclusions:There is a pronounced association between socioeconomic development status and burden of common cancers of the gastrointestinal tract.Data of our research are valuable for policymakers to implement cost-effective interventions for gastrointestinal tract cancers. |