Effects Of Fermented Chinese Herbal Medicine On Growth Performance And Blood Biochemical Indexes Of Weaned Piglets

The purpose of this study was to investigate the effect of fermented Chinese herbal medicine(trade name: Tikangtai)on the growth performance and blood biochemical indexes of weaned piglets.162 Du-grown ternary hybrid piglets were selected.The initial weight of the piglets was between 6kg and 8kg.The ratio of male to female was half,and piglets were randomly assigned to three groups according to the principle of similar body weight.Each group had 6 replicates,and each replicate had 9 piglets.The control group was fed the basal diet,the experimental group 1 was fed the basal diet supplemented with 0.3% of Chinese herbal medicine,and the experimental group 2 was fed the basal diet with 0.5% of Chinese herbal medicine.The pre-feeding period is 3 days,and the official period is 21 days.From the beginning of the test period,the feed intake of the piglets and the diarrhea status of the piglets were recorded every day,and on the 21 st day of the test,a piglet was randomly selected from each replicate group for blood collection from the anterior vena cava for the determination of blood biochemical indicators,and then slaughtered for liver,The organs such as pancreas,heart,spleen,and kidney were used to measure the organ index of piglets,and about 6 cm of the middle jejunum was taken for the determination of intestinal mucosal immune indexes and antioxidant indexes.The results showed that:1.Effects of fermented Chinese herbal medicine on growth performance of weaned pigletsCompared with the control group,the addition of 0.3% and 0.5% tikantha to the diet of weaned piglets significantly increased the final weight,average daily feed intake and average daily gain of weaned piglets(P<0.05).The effect of group 2 was better than that of group 1;however,the ratio of feed to meat did not change significantly with the increase of tikantai addition amount(P>0.05).2.Effects of fermented Tikangtai on organ index of weaned piglets.Compared with the control group,the addition of 0.3% and 0.5% Tikangtai in the diet of weaned piglets had no significant effect on the indexes of the heart,liver,pancreas,spleen,kidney and other organs of weaned piglets(P>0.05).3.Effects of fermented Chinese herbal medicine on serum biochemical and antioxidant indexes of weaned pigletsCompared with the control group,the contents of Immunoglobulin M(Ig M)and Immunoglobulin G(Ig G)in the serum of weaned piglets increased significantly(P<0.01)when 0.3% and 0.5% Tycoon was added to the diet,and the serum Interleukin-1β(IL-1β),Lipopolysaccharide(LPS)and intestinal permeability D-lactic acid(D-La)in serum decreased significantly(P<0.01).Adding 0.3% and 0.5% Tikangtai to the diet,respectively,significantly decreased the serum levels of glutathione peroxidase(GSH-Px)and malondialdehyde(Malondialdehyde)in weaned piglets.MDA)content(P<0.01),and for the content of MDA in serum,the addition of 0.3% Tikangtai decreased more significantly than the addition of 0.5% Tikangtai.4.Effects of fermented Chinese herbal medicine on jejunal immune indexes of weaned pigletsCompared with the control group,the addition of 0.3% and 0.5% Tikangtai in the diet could significantly increase the contents of Ig A,Ig M and Ig G in the jejunal mucosa of weaned piglets(P<0.01).,the dosage of 0.5% Tikangtai was better than 0.3%;the content of secretory immunoglobulin A(Secretory immunoglobulin A,SIg A)in the jejunal mucosa of weaned piglets was significantly increased(P<0.01),and 0.3% The effect of Tiekangtai was better than that of 0.5%;but it could significantly reduce the content of IL-1β and IFN-β in the jejunal mucosa(P<0.05),and the content of TNF-α would also decrease.Among them,the content of IL-1β decreased more obviously when 0.3% Tikangtai was added,while the content of IFN-β decreased with the increase of Tikangtai addition.5.Effects of fermented Chinese herbal medicine on antioxidant indexes of liver and jejunum mucosa of weaned piglets.Compared with the control group,the content of GSH-Px in the liver of weaned piglets increased significantly when 0.5% Tikangtai was added(P<0.05),but decreased when 0.3%Tikangtai was added;Tikangtai can significantly reduce the content of MDA in liver(P<0.05),but there is no significant effect when adding 0.5%t concentration of Tikangtai(P>0.05);adding 0.3%,0.5% concentration of Tikangtai can significantly reduce the activities of T-AOC and SOD in the liver of weaned piglets(P<0.05).The content of GSH-Px in the jejunal mucosa of weaned piglets was significantly decreased when 0.5% of Tikangtai was added to the diet(P<0.01);the contents of T-AOC,SOD and CAT in the jejunal mucosa of weaned piglets After adding different concentrations of tikangtha,the change was not significant(P>0.05).It can be seen that the addition of different concentrations of fermented Chinese herbal medicine(Chinese herbal medicine)to the diet of weaned piglets can significantly improve the growth performance of weaned piglets,reduce the diarrhea rate of piglets,enhance the intestinal immunity of piglets,and improve the liver tract of piglets.Antioxidant capacity.At the same time,the test results showed that adding 0.3% fermented Tikangtai and 0.5%fermented Tikangtai to the diet of weaned piglets had no significant difference in the growth performance of piglets.Therefore,in production practice,it is recommended that 0.3% of fermented Chinese herbal medicine(Chinese herbal medicine)be added to the diet of weaned piglets.