Software And Hardware System Design Of Biochemical Detector Based On Microfluidic Technology

Whether it is disaster rescue and battlefield treatment,or epidemic prevention and community outpatient inspection and other application conditions,it is of vital importance to quickly obtain the relevant biochemical indicators of the injured patients.Biochemical detectors in large and medium-sized hospitals are difficult to apply to disasters and field environments due to their large size and high environmental conditions.Fully automated biochemical detectors are mostly complicated to operate and expensive to manufacture,and are difficult to spread to primary-level medical institutions.Therefore,it is of great social significance and practical value to develop a biochemical detector with multiple parameters,easy operation,low consumption,quick detection and small volume in combination with microfluidic technology,so as to adapt to field diagnosis and treatment,improve the strength of primary medical treatment and improve the medical structure.Aiming at the application requirement that the multi-parameter biochemical indexes of the injured patients can be obtained in the field and in the community clinic,the paper carried out the research on the software and hardware system technology of the biochemical detector based on the micro-flow control technology.A design scheme for the detection system based on the centrifugal microfluidic reagent tray,LED and photosensitive tube is proposed,which meets the requirement for the biochemical detection system to be miniaturized while maintaining high accuracy of rapid detection.According to the detection principle and the overall technical scheme,an embedded software and hardware system with S3C2440 as the core is designed,so that the instrument has the characteristics of small size and high performance;the human-machine interaction interface with high availability is designed to reduce the user's learning cost and improve the user's operating efficiency;the basic functional test and clinical comparison test have been completed.The obtained data shows that the microfluidic biochemical detector developed is stable in operation,the repeatability of the measurement results is good,and the detection accuracy and detection efficiency basically meet the clinical application requirements.This thesis mainly completes the work as follows:(1)Check the development status of semi-automatic biochemical analyzers and summariz the shortcomings of several commercial instruments.The relevant materials of microfluidic technology and biochemical detection technology are analyzed to determine the key research objectives and contents of this article.(2)The principle of spectrophotometry and microfluidic sampling are studied,and the design scheme of the detection system based on centrifugal microfluidic reagent tray,LED and photosensitive tube is proposed.(3)According to the photoelectric detection design and the functional requirements of the instrument,the detection system circuit and other functional circuit solutions are proposed to complete the hardware selection and realize the specific circuit design.(4)According to the hardware system scheme,propose an embedded software system scheme;complete the drive software design of the hardware device and the application software design of the instrument function.(5)According to the detection process,analyze the operations required by the user at each step,complete the design of the human-computer interaction interface,and improve the user's operating efficiency through the optimized layout of the controls.(6)Integrate the hardware system and the software system to complete the instrument assembly;conduct instrument debugging and clinical comparative tests.The experimental results show that the microfluidic biochemical detector developed basically meets the clinical application needs.