Analysis Of Related Factors Of Postoperative Parenteral Fistula In Colorectal Cancer

Objective:To analyze the risk factors of parenteral fistula after radical surgery for colorectal cancer,and to explore its causes and treatment strategiesMethods:The clinical data of 473 patients with colorectal cancer who underwent radical surgery from January 2017 to January 2020 in the Department of emergency surgery and high tech gastrointestinal surgery of the First Affiliated Hospital of Anhui Medical University were selected,The general clinical data of all the subjects included the patient’s gender,age,diabetes,hypertension,preoperative hemoglobin level,preoperative total protein level,tumor location,operation method,operation duration,postoperative pathological stage,etc.the diagnosis of parenteral fistula was based on the patient’s clinical signs and targeted auxiliary examinations.The collected preoperative hemoglobin and preoperative total protein were the last before the operation The results of one blood test.The extraction of operation time is counted from the beginning of anesthesia to the end of anesthesia.The postoperative pathology is divided into three stages: low,medium and high。Results:After the inclusion and exclusion criteria,a total of 473 patients were enrolled in this study.There were 31 cases of postoperative intestinal fistula and 442 cases without postoperative intestinal fistula.There were 260 males（54.96%）and 213 females（45.04%）;A total of 74 patients（15.64%）had diabetes before operation,and 399 patients（84.36%）did not have diabetes.There were 63 patients with hypertension（13.32%）and 410 patients without hypertension（86.88%）.The general clinical data of the two groups were analyzed.The results showed that:（1）there was no significant difference in gender,preoperative hypertension and preoperative total protein level between the two groups.The results showed that there was no significant difference in gender（P = 0.698）,preoperative hypertension（P = 0.635）,preoperative white protein level and（P = 0.168）;（2）the age（p=0.002）and duration of operation（p<0.001）of patients with postoperative intestinal fistula were significantly higher than those without intestinal fistula,and there were significant differences in preoperative diabetes mellitus（p=0.039）and preoperative hemoglobin level（p=0.002）,with statistical significance（p< 0.05）.Conclusion:1.In colonic malignant tumors,the location of the tumor had no significant difference in the occurrence of postoperative intestinal fistula;In rectal malignancies,there is a significant difference between rectal cancer above peritoneal reflexes and rectal cancer below peritoneal reflexes,which needs special attention2.After comparing the general clinical data of patients,it is found that the age,preoperative hemoglobin level,operation mode and operation duration of patients are independent risk factors for postoperative extraintestinal fistula of colorectal cancer.Individualized operation schemes can be adopted for different patients according to the above factors to reduce the risk of postoperative extraintestinal fistula of colorectal cancer,Improve the prognosis of patients and reduce the length of hospital stay and clinical expenses...