Risk Factors Of Persistent Multiple Ground Glass Nodules In Lung

Objective:To explore the risk factors for the occurrence of persistent multiple ground glass nodules by analyzing the general data and laboratory indicators of patients with persistent multiple ground glass nodules on lung CT.Methods:A total of 76 patients with multiple ground glass nodules diagnosed by lung CT in the Department of Respiratory Medicine or the Department of Thoracic Surgery of the First Hospital of Jilin University from April 2020 to December 2021 were selected,and selected 76 patients who underwent physical examination at the Physical Examination Center of the First Hospital of Jilin University from April 2020 to December 2021.The general data and laboratory indicators of the patients were statistically analyzed.The two groups were compared to analyze the risk factors for the occurrence of persistent multiple ground glass nodules.Results:In this study,there were no significant differences in occupational risk factors exposure and smoking history between patients with multiple ground glass nodules and those without multiple ground glass nodules（P>0.05）,and there were statistically significant differences in age,gender,pulmonary symptoms,family history of lung cancer and cooking history between the two groups（P <0.05）.There were no significant differences in serum HB,WBC,PLT,NE,LY and RDW between 2 groups（P >0.05）,and the serum NLR level in patients with nodules was significantly higher than that in patients without nodules,the difference was statistically significant（P<0.05）.We further conducted Logistic regression analysis on the indicators with statistically significant differences,and the results showed that pulmonary symptoms,family history of lung cancer,cooking history,and high NLR were independent risk factors for persistent multiple ground glass nodules in lung imaging（P<0.05）.Conclusions:1.The patients with nodules were older than those without nodules,and there were more female patients than male patients.2.Pulmonary symptoms,family history of lung cancer,cooking history and high NLR were independent risk factors for persistent multiple ground glass nodules in lung imaging.