A Study On Characteristics About The External Performance Of Meridians Of Polycystic Ovary Syndrome

Objectives:Observing the characteristic features of the 12 meridians below the elbows and knees of patients who have PCOS and using the meridian-acupoint diagnosis method as the research means,to conduct a comparative study on the correlation between meridian syndrome differentiation and syndrome differentiation of zang-fu organs as well as the symmetry of the left and right sides of the same meridians.The aim of this study is to enrich the clinical diagnosis and treatment methods of acupuncture and moxibustion and improve the accuracy of clinical diagnosis.Methods:Volunteers were divided into two groups:the experimental group（PCOS patients）and the control group（healthy volunteers）.To investigate the twelve meridians below the elbows and knees by means of observation,inquiry and palpation from top to bottom and from outside to inside of the body.The pain threshold of tenderness points was measured with an analgesy-Meter.The distribution rules of abnormal manifestations of acupoints were summarized by T test,?^（17）test,nonparametric rank-sum test and analysis of variance were used to compare the differences in tenderness and acupoints morphological abnormalities between the two groups.Binary Logistics regression analysis,Spearman correlation analysis and Pearson correlation analysis were used to explore the correlation and influencing factors.Results:1.The baseline was balanced and comparable（P>0.05）.2.The positive rate of spleen meridian of PCOS patients was significantly higher than that of healthy volunteers（P<0.05）.3.Comparison of the frequency of tenderness of key acupoints（the sum of the positive cases in the two groups is more than 5）,the occurrence rate of SP6（left）in the disease group is higher than that in the healthy group（P<0.05）.4.The mean value of pain threshold in the disease group was higher than that in the healthy group,and LU6（right）,LI4（right）,SP9（left）,SP9（right）,SP6（left）were significantly higher（P<0.05）;For the morphological abnormalities rate of acupoints,LU6（right）,SP9（right）,SP6（left）,SP6（right）,SP8（right）and SP7（right）were more obvious in the disease group than in the healthy group,and the difference was statistically significant（P<0.05）.5.There was a weak positive correlation between mean value of pain threshold and BMI,that is,the higher BMI,the higher mean value of pain threshold and the lower sensitivity（P<0.05）.6.The incidence of morphological abnormalities of spleen meridian in the disease group was higher than that in the healthy group（P<0.001）.The incidence ofmorphological abnormalities in LU6（right）,SP9（right）,SP6（left）,SP6（right）,SP8（right）,and SP7（right）points in the disease group was higher than that in the healthy group（P<0.05）.7.BMI of the syndrome of spleen and kidney deficiency was significantly higher than that of the other three syndrome types（P<0.05）,but there was no statistical significance compared with liver depression and spleen deficiency syndrome;About mean value of pain threshold,the syndrome type of Qi stagnation and blood stasis,LR3（left）and LR3（right）was significantly higher than that in the other three syndromes（P>0.05）.8.There was no significant difference in menarche between spleen and kidney deficiency and other syndromes（P>0.05）;The positive frequency of meridians had no significant correlation with disease duration,BMI,syndrome types and menarche（P>0.05）;The lung meridian was correlated with the syndrome of spleen and kidney deficiency（P<0.05）;The left SP9 was correlated with the syndrome of spleen and kidney deficiency（P<0.05）.9.Correlation analysis of meridian syndrome differentiation and syndrome differentiation of zang-fu organs:the liver meridian was positively correlated with the spleen meridian and the large intestine meridian（P<0.05）;There is obvious correlation between the left and right sides of the key acupoints.There is a positive correlation between the lung meridian（LU6）and the large intestine meridian（LI3 and LI10）.In addition,there is a positive correlation between the large intestine acupoint（LI10）and the liver meridian acupoint（LR3）.Conclusions:1.The positive rate of spleen meridian in PCOS is higher than that in healthy group,suggesting that spleen meridian is specific for PCOS.2.The elevated pain threshold in PCOS patients may be related to the passivation of pain caused by glucose metabolism and hormone secretion disorders.So in this study,pain threshold acupoints cannot be used to judge the severity of the condition.The occurrence rate of morphological abnormalities along the meridian is more valuable in the diagnosis of PCOS.Among the 12 meridians,the occurrence rate of morphological abnormalities in the spleen meridian is specific for PCOS,and specific acupoints are SP9,SP6,SP8,and SP7,etc.4.PCOS leads to increased BMI in patients with spleen and kidney deficiency syndrome.5.The results showed that there was a high correlation between the lung meridian and the syndrome type of spleen and kidney deficiency,indicating that there was no direct correspondence between the syndrome differentiation of zang-fu organs and the meridians in this study.