| Objective:This project intends to comprehensively evaluate the clinical efficacy of Professor Xiong Dajing’s empirical prescription Liyan prescription in the treatment of acute pharyngitis(lung and stomach heat syndrome),and compare it with Lanqin oral liquid to observe the difference in clinical efficacy of the two,aiming to inherit the experience of famous old Chinese medicine practitioners,and give play to the advantages of famous old Chinese medicine experience in the treatment of acute pharyngitis.Methods: Sixty patients with acute pharyngitis(lung and stomach heat syndrome)who met the inclusion and exclusion conditions were selected and randomly divided into the treatment group and the control group in a 1:1 ratio.The treatment group took Liyan prescription instead of decoction,and the control group took Lanqin oral liquid.2 times were followed up during treatment,and VAS scores and pharyngeal hyperemia signs scores were collected before and after treatment for symptoms(sore throat,dry throat,pharyngeal burning)in 2 groups.Before treatment,the general baseline data of the two groups were compared,and the VAS score,symptom total score and pharyngeal congestion sign score of each symptom were compared within each group before and after treatment,and the intergroup comparison was conducted to systematically evaluate the advantages of famous old Chinese medicine empirical prescription in the treatment of acute pharyngitis.Results: 1.Demographic data of the two groups were compared,P > 0.05,showing no statistical difference.2.VAS score,symptom total score and pharyngeal hyperemia sign score before treatment were compared between the two groups,and there was no statistical difference(P > 0.05).3.Intra-group comparison between the two groups: VAS score,total symptom score and pharyngeal hyperemia signs of each symptom in the treatment group and the control group before and after treatment were compared,and P values were all < 0.001,showing significant differences.4.Comparison between the two groups: after treatment,VAS score,total symptom score and pharyngeal hyperemia signs of the two groups were compared: in terms of pharynx pain,P=0.025 < 0.05,showing significant differences;P= 0.101>0.05,there was no significant difference in pharynx trunk.In terms of pharyngeal burning,P=0.031 < 0.05,there was a significant difference;In terms of total symptom score,P=0.004 < 0.05,there was a significant difference;P=0.046 < 0.05 in pharyngeal hyperemia signs,there is a significant difference.Conclusion: 1.The treatment group(Liyan Formula)and the control group(Lanqin Oral Liquid)had significant improvement effect on the clinical symptoms and signs of acute pharyngitis;2.The overall efficacy of Liyan Formula in the treatment of acute pharyngitis(lung and stomach solid heat syndrome)is better than that of Lanqin Oral Liquid,which is more obvious in improving pharyngeal pain,pharyngeal burning feeling and pharyngeal congestion signs. |