The Diagnostic Value Of SWI In Acute Cerebral Infarction With CMBs And Analysis Of Related Risk Factors

ObjectiveTo explore whether the susceptibility weighted imaging sequence has important value in the diagnosis of cerebral microhemorrhage(CMBs),and to study the incidence,distribution and related risk factors of CMBs in patients with acute cerebral infarction.In order to provide feasible Suggestions for clinical treatment and secondary prevention of patients with cerebral infarction.Materials and methodsA total of 102 patients(non-cardiogenic)with acute cerebral infarction who were admitted to the neurology department of affiliated hospital of taishan medical college between January 2018 and October 2018 and had complete data were randomly selected.The onset time was all within 72 h.According to the results of the sw imaging,the patients were divided into the positive group and the negative group,and the number and location of CMBs lesions were counted,The general clinical data,biochemical indexes and imaging manifestations of the two groups were compared,and univariate analysis and multivariate logistic regression analysis were performed.ResultsAmong 102 patients with acute cerebral infarction,there were 59 male patients and 43 female patients,whose age ranged from 40 to 85 years old,with an average age of59.3±11.7 years old.There were 34(33%)cases of smoking,40(39%)cases of drinking,51(50%)cases of hypertension,29(28%)cases of diabetes,and 85(83%)cases of white matter lesions.After the scan of the SW imaging,a total of 34(33.3%)cases with CMBs were detected,among which 22(21.6%)cases were mild,8(7.8%)cases were moderate,and 4(3.9%)cases were severe.There were 172 CMBs foci in total,among which 96(55.8%)were deep white matter which was in the most distributed,followed by 55(32.0%)were in the cerebral lobe and 21(12.2%)were in the infratentorial.Results of univariate analysis showed that there were statistically significant differences between the two groups in age [(65.1 10.55)vs(56.4 11.30),P <0.001],history of hypertension(70.6%vs39.7%,P = 0.003),systolic blood pressure at admission [(158.82 19.67)vs(133.90 12.87),P<0.001],white matter lesions [(3.97 1.34)vs(1.72 1.63),P <0.001],Hcy[(17.35 4.14)vs(14.32 3.31),P<0.001].Results of multivariate logistic regression analysis showed that age,history of hypertension,systolic blood pressure at admission,white matter lesions and Hcy were the risk factors for CMBs(P < 0.05),among which age was an independent risk factor for CMBs.ConclusionCMBs has become an important clinical biomarker of cerebrovascular diseases,which is the result of focal deposition of trace hemosiderin,indicating damage of cerebrovascular and destruction of blood-brain barrier.