Correlation Analysis Between Coronary Artery Disease And ST-T Changes Of ECG

Objectives Using 256-layer coronary CT angiography(CCTA)to investigate the correlation between the degree of coronary artery stenosis,the number of lesions,the nature of plaque,the score of calcification and ST-T changes in routine electrocardiogram(ECG).Methods 280 patients with coronary heart disease admitted to the Affiliated Hospital of North China University of Science and Technology from January 2019 to July 2020 were selected.256 slice coronary CT angiography(CCTA),routine electrocardiogram(ECG)and digtal subtraction angiography(DSA)were used in quiet environment.The general clinical data,past medical history and biochemical examination of all patients were recorded.CCTA examination results:according to the degree of coronary stenosis,the patients were divided into moderate,severe and occlusion groups;according to the number of coronary artery lesions,the patients were divided into 1,2 and 3 groups;according to the nature of plaque,the patients were divided into non calcification,calcification and mixed groups;according to different calcification scores,the patients were divided into 0-99 group,100-399 group and≥400 group.Chi square test was used to compare the positive detection rate of ST-T changes in ECG among patients with different degree of coronary artery stenosis,different number of lesions,different nature of plaque and different calcification score.Results 1 The positive detection rate(42.1%vs 60.3%vs 66.7%)of ST-T changes in ECG among different degrees of coronary stenosis(moderate,severe and occlusive)was statistically significant(χ~2=9.756,P=0.008);multiple comparisons of ST-T changes in ECG of different stenosis degrees showed that the positive detection rate of ST-T changes in ECG between moderate stenosis group and severe stenosis group was statistically significant(χ~2=8.589,P=0.003);the positive detection rate of ST-T changes in ECG between moderate stenosis group and occlusion group(χ~2=3.232,P=0.072),severe stenosis group and occlusion group(χ~2=0.235,P=0.628)was not statistically significant.2 The positive detection rate(62.8%vs 47.8%vs 40.7%)of ST-T changes in ECG among different coronary artery lesions(1vessel,2vessel and 3vessel)was statistically significant(χ~2=9.549,P=0.008);multiple comparison of ST-T changes in ECG with different number of lesions showed that the positive detection rate of ST-T changes in ECG between1 vessel lesion group and 3 vessel lesion group(χ~2=8.028,P=0.005)was statistically significant;the positive detection rate of ST-T changes in ECG between 1 vessel lesion group and 2 vessel lesion group(χ~2=4.895,P=0.027),2 vessel lesion group and 3 vessel lesion group(χ~2=0.742,P=0.389)was not statistically significant.3 There was no significant difference in the positive detection rate of ST-T changes in ECG among different plaque properties(χ~2=1.581,P=0.454).4 There was no significant difference in the positive detection rate of ST-T changes in ECG among different calcification scores(χ~2=1.538,P=0.463).5 The positive detection rate(45.3%vs 89.8%vs 60.0%)of ST-T changes in ECG among different degrees of coronary stenosis(moderate,severe and occlusive)in one vessel lesion group was significantly different(χ~2=25.094,P<0.001);multiple comparisons of ECG ST-T changes in different stenosis degrees of one vessel disease showed that the positive detection rate of ECG ST-T changes in moderate stenosis group and severe stenosis group was statistically significant(χ~2=25.108,P<0.001);the positive detection rate of ECG ST-T changes in moderate stenosis group and occlusion group(χ~2=0.406,P=0.524),severe stenosis group and occlusion group(χ~2=3.570,P=0.059)was not statistically significant.The positive detection rate(29.0%vs 54.5%vs83.3%)of ST-T changes in ECG among different degrees of coronary stenosis(moderate,severe and occlusive)in two vessel lesion group was statistically significant(χ~2=8.415,P=0.015);multiple comparisons of ECG ST-T changes in different stenosis degree of two vessel disease showed that the positive detection rate of ECG ST-T changes in moderate stenosis group and occlusion group(χ~2=6.302,P=0.012)was statistically significant;the positive rate of ST-T changes in ECG in moderate stenosis group and severe stenosis group(χ~2=5.207,P=0.022),the severe stenosis group and occlusion group(χ~2=1.833,P=0.176)was not statistically significant.The positive detection rate of ST-T changes in ECG among different degrees of coronary stenosis in three vessel disease group,the difference was not statistically significant(χ~2=2.119,P=0.347).Conclusions 1 The degree of coronary artery stenosis is different,the positive rate of routine electrocardiogram ST-T change is different,the more serious the stenosis,the higher the positive detection rate of ST-T changes.2 The number of coronary artery lesions is different,the positive detection rate of routine electrocardiogram ST-T changes is different,the more the number of lesions,the lower the positive detection rate of ST-T changes.3 There is no correlation between the characteristics of different plaques and calcification score and the positive detection rate of ST-T changes in conventional electrocardiogram.Figure 9;Table 13;Reference 106...