Acupuncture “12 Acupoints Of Madanyang Tianxing” Combined With Estazolam Clinical Observation Of Sleep Disorder After Chemotherapy For Tumor

ObjectiveThis study is to observe the clinical observation of acupuncture "Ma Danyang Tianxing Twelve Acupoints" in the treatment of sleep disorders after chemotherapy for malignant tumors.By comparing the Pittsburgh sleep quality index and TCM clinical symptom evaluation scores before and after treatment between the acupuncture group and the control group,it provides the basis for the treatment of improving the clinical efficacy of cancerinduced insomnia.To observe the correlation between the occurrence of cancer-induced insomnia and psychosocial psychology by Zung Self-Rating Anxiety Scale(SAS)and Zung Self-Rating Depression Scale(SDS),and to provide a new idea for future treatment to attach importance to emotional factors.MethodsThrough the way of clinical control observation,acupuncture "Madanyang Tianxing Twelve Acupoints" as an intervention measure,according to the willingness of patients meeting the diagnostic criteria to receive treatment,were divided into acupuncture group and control group to receive the corresponding treatment.The control group was treated with oral esazolam tablets,and the acupuncture group was treated with "12 acupoints of Madanyang Tianxing" on the basis of oral esazolam.Acupuncture group: 50 patients were treated with flim-needle acupuncture and estazolam clinically.Control group: 50 patients were treated with estazolam tablets.Patients in the 2 groups were evaluated at the time of inclusion and after treatment.It was planned to conduct in-depth analysis from the Pittsburgh Sleep Quality Index(PSQI),TCM clinical symptom evaluation scale score and multiple perspectives,and collect clinical data to provide a basis for evaluating the effectiveness of acupuncture.Zung Self-Rating Anxiety Scale(SAS)and Zung Self-Rating Depression Scale(SDS)were used to observe the correlation between cancer-related insomnia and affective factors,and to observe the regulating effect of acupuncture on affective factors,so as to provide reference for improving the clinical efficacy and pathogenesis of cancer-related insomnia.ResultsIn this clinical study,a total of 100 patients with sleep disorders after chemotherapy for malignant tumors were included,of which 5 cases were excluded,and the final effective cases were 95.According to the analysis of the results,the results of the two groups were better than those before treatment,but the effect of acupuncture group was more significant(P=0.0377).After treatment,the total PSQI scores in both groups were lower than before,but the decrease was more obvious in acupuncture group(P=0.0002<0.05).After treatment,the intra-group comparison of PSQI scores in 2 groups was significantly decreased(P<0.05),and there were no significant differences in sleep quality,time to fall asleep,sleep time,sleep efficiency,sleep disorders and hypnotic drugs reduction(P>0.05).However,the acupuncture group had better performance in daytime dysfunction score(P<0.05).Compared with the control group(38.00%),the acupuncture group had a more significant effect on improving the scores of TCM clinical symptom evaluation scale(68.89%)(P=0.0267).Meanwhile,the acupuncture group had a curative effect on improving the state of anxiety and depression(P<0.05),while the curative effect before and after the control group was not statistically significant.Therefore,the acupuncture group had a better clinical effect on improving the quality of life of patients.There was no statistical difference in the safety indexes between the two groups before and after treatment.No serious adverse reactions occurred in the two groups.ConclusionThis study proved that,for patients with cancer-related insomnia,acupuncture " Ma Danyang Tianxing 12 points" combined with estazolam tablets is more significant than the use of estazolam tablets alone.Patients with acupuncture group was at the same time to improve cancerrelated PSQI score,anxiety,depression,Chinese medicine symptom score also have relatively good effect,can improve the quality of sleep,improve sleep disorders,as well as the symptoms such as diarrhea,constipation,chest tightness,fatigue all have different degrees of improvement,so as to improve the quality of life of patients with malignant tumor,improve malignant tumor after chemotherapy for comprehensive treatment of traditional Chinese medicine complications provides a certain reference significance,can further research and application in clinic.