| Objictive The purpose of this study is to study the classification of TCM constitution of perimenopausal women in Beijing and Guangzhou in order to understand the general situation,constitutional distribution and life quality of perimenopausal syndrome in Beijing and Guangzhou,so as to provide treatment of perimenopausal syndrome based on constitutional health maintenance,and to provide TCM theoretical foundation for perimenopausal women’s health management.Method According to the research methods of clinical epidemiology,this study conducted a questionnaire survey on 438 cases of perimenopausal women living in communities,schools,enterprises and institutions in Beijing and 384 cases of perimenopausal women in Guangzhou,by random sampling and serial samples research.Information including the general situation,the scale of TCM constitutional quality and the scale of life quality in menopausal period(Men QOL scale)is collected and compared to find differences between Beijing and Guangzhou.Results1.In general,the research of perimenopausal women in Beijing bases on 438 cases in total,with an average age of 48.13 ± 5.32 years.The average age of menopause is 49.83 ± 2.9 years,and the average age of menstrual disorders is 47.62 ± 4.12 years;while the research in Guangzhou is based on 384 cases in total,with an average age of 47.54 ± 5.46 years.The average age of menopause is 49.34 ± 2.11 years,and the average age of menstrual disorders is 47.32 ± 2.37 years.The differences between the two groups in general conditions such as age,marriage age,menopause age,age of menstrual disorders,occupation,life and work pressure are not statistically significant(P> 0.05),so data of these two groups are comparable.2.Beijing group includes 144 cases of mild constitution,96 cases of Yangdeficiency,21 cases of Qi deficiency,3 cases of Yin deficiency,41 cases of phlegm and dampness,10 cases of Qi stagnation,7 cases of blood stasis,63 cases of damp heat,53 cases of special quality;Guangzhou group includes150 cases of mild constitution,26 cases of Yang deficiency,26 cases of Qi deficiency,25 cases of Yin deficiency,24 cases of phlegm and dampness,10 cases of Qi stagnation,26 cases of blood stasis,72 cases of dampheat,25 cases of special quality.Mild constitution is a common constitution for perimenopausal women in Beijing and Guangzhou.Theproportion of mild constitution in Beijing group is 32.9%,and Guangzhou group is 39.1%.For biased constitutions,the qualities of Yang deficiency,damp heat,special quality,phlegm and dampness are the most common in Beijing group,while damp heat,Qi deficiency,Yang deficiency,Yin deficiency,phlegm and dampness,blood stasis,special quality is more common in Guangzhou group.According to statistics analysis of different ages of two groups of perimenopausal women in Beijing and Guangzhou,there is no statistical difference between the proportions in four age periods and there is no significant difference in the constitutional ratios of the four age periods.3.Data in vasomotor symptoms dimensions,sexual life dimensions and life quality scores for Beijing group are all less than Guangzhou group,with statistical difference(P <0.05),while there is no statistical significance between the two groups in other dimensions.There is statistical difference between Beijing and Guangzhou life quality score for people in mild constitution.The score of life quality for people in mild constitution in Beijing group is less than that of Guangzhou group,which means thatpeople in mild constitution in Beijing live better than Guangzhou(P < 0.05).There is no statistical significance in scores of life quality for people in the rest constitutions of the two groups.4.The occupation,personality and physical condition impact the life quality of people of Beijing group,Guangzhou group and all the surveyed cases.People who is unemployed,semi-physical,extroverted,and in worse physical condition,live worse lives.Age,marriage age,menstrual cycle,childbirth times are positively correlated with life quality score,that is,life quality of people with older age,older marriage age,longer menstrual cycle,more childbirth times is worse.And the rest of general factors are not statistically significant.5.There are significant differences in life quality scores of mild constitution and biased constitution for Guangzhou group,Beijing group,and general population.The results show that life quality scores of mild constitution is less than biased constitution,which is statistically different(P <0.05).The single physique,two kinds of physiques,a variety of physiquesof Beijing,Guangzhou and the general population have statistically significant differences with life quality scores.Pairwise comparisons of life quality scores with the assistance of ridit show the result as below: Beijing group: single physique <2 kinds of physiques<various physiques,Guangzhou group:(single physique = 2 kinds of physiques)<various physiques,general:(single physique = 2 kinds of physiques)<various physiques,which is statistically difference.Conclusion1.Mild constitution is a common constitution for perimenopausal women in Beijing and Guangzhou.For biased constitutions,the qualities of Yang deficiency,damp heat,special quality,phlegm and dampness are the most common in Beijing group,while damp heat,Qi deficiency,Yang deficiency,Yin deficiency,phlegm and dampness,blood stasis,special quality is more common in Guangzhou group.There is no significant difference among constitutions of women in various ages.2.Life quality of perimenopausal women in Beijing is slightly better than Guangzhou.Life quality scores of Beijing in vasomotor symptoms dimensions and sex life dimensions are all higher than Guangzhou.Perimenopausal women in mild constitution in Beijing live better than Guangzhou,while there is no significant difference for biased constitution.3.Age,marriage age,menstrual cycle,childbirth times,occupation,personality,physical condition impact people’s life quality.People who is unemployed,semi-physical,extroverted,in worse physical condition,with older age,older marriage age,longer menstrual cycle,more childbirth times live worse lives.4.Perimenopausal women with various constitutions live worse lives than women with single constitution and two kinds of constitutions. |