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The Value Of Automated Office Blood Pressure In Diagnosis Of Hypertension And Evaluation Of Antihypertensive Effect

Posted on:2022-06-03Degree:MasterType:Thesis
Country:ChinaCandidate:H Q HuangFull Text:PDF
GTID:2504306554979199Subject:Internal medicine (cardiovascular disease)
Abstract/Summary:PDF Full Text Request
Objective:To assess the value of automated office blood pressure(AOBP)in diagnosis of hypertension and antihypertensive effect compared with office blood pressure(OBP),home blood pressure(HBP)and 24-hour ambulatory blood pressure(ABP).To evaluate the correlation between AOBP with left ventricular mass index(LVMI)in hypertensive patients.Methods:A total of 118 consecutive hypertensive outpatients were enrolled,55 men and 63 women,with a mean age of 56.1±12.8 years,who visited the Department of Cardiovascular Medicine of a Grade-A tertiary hospital in Fujian during the period of August 2019 to February 2021.The AOBP,OBP and HBP were measured by using the semiautomatic oscillometric Omron HEM-7200 blood pressure device and the 24-hour ABP was recorded in those participants.LVMI was made by color Doppler echocardiography.Results:1.The mean blood pressure readings were 145.91±14.52/85.29±10.04 mm Hg for OBP,139.97±13.64/82.93±10.10 mm Hg for AOBP,129.85±10.73/81.54±9.25 mm Hg for HBP and 128.65±13.44/80.52±10.42 mm Hg for awake-ABP.Both systolic blood pressure(SBP)and diastolic blood pressure(DBP)of AOBP are lower than that measured by OBP and higher than that measured by awake-ABP and SBP of AOBP was higher than that measured by HBP(p<0.05).2.The optimal cutoff value of AOBP for the diagnosis of hypertension was136.67/85.67 mm Hg(sensitivity 51.95%,specificity 82.93%)by drawing receiver operating characteristic(ROC)curve using awake-ABP as the gold standard.And the Area Under Curve(AUC)of SBP measured by AOBP was higher than that of OBP and lower than that of HBP.3.The heart rate measured by OBP or AOBP was significantly higher than that measured by HBP and awake-ABP(74.88±11.66 or 74.92±11.17 vs 70.48±9.67 and72.55±9.49 bpm,p< 0.05 for both).And the heart rate measured by HBP was lower than that measured by awake-ABP(70.48±9.67 vs 72.55±9.49 bpm,p<0.05 for both).4.DBP of HBP and both SBP and DBP of awake-ABP were positively associated with LVMI(r=0.239 for DBP of HBP,r=0.296 for SBP of awake-ABP,r=0.286 for DBP of a-ABP,p<0.05 for all).However,no correlation was found between OBP and AOBP with LVMI.Conclusions:1.AOBP can improve,but does not eliminate,white coat effect.And the cutoff point for the diagnosis of hypertension by AOBP was 136.67/85.67 mm Hg in our study.2.The diagnostic efficacy and correlation with left ventricular quality index for AOBP is inferior to that of HBP and awake-ABP.3.White coat effect of heart rate for OBP and AOBP was presented in hypertensive patient,it can’t be eliminated by AOBP as blood pressure.
Keywords/Search Tags:Automated office blood pressure, White coat effect, Hypertension, Heart rate, Left ventricular mass index
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