Study On TCM Syndrome Types Of H-type Hypertension Complicated With Coronary Heart Disease

Objective: Objective to explore the distribution of TCM Syndrome Types in patients with H-type hypertension complicated with coronary heart disease,and to provide reference for the next step of targeted clinical research on H-type hypertension complicated with coronary heart disease.Methods:The patients with H-type hypertension and coronary heart disease who were hospitalized in the First Affiliated Hospital of Heilongjiang University of traditional Chinese medicine from September 2019 to December2020 were selected as the research objects.The patients’ age,gender,systolic blood pressure,diastolic pressure,course of hypertension,information of four diagnosis of TCM were collected during admission,and TCM syndrome differentiation was carried out,and the results of TCM syndrome differentiation were grouped.The differences in sex distribution,course of hypertension,blood pressure classification and homocysteine levels were compared in each group,and the preliminary conclusions were drawn.Results:1.128 cases of H-type hypertension complicated with coronary heart disease were included in this study.According to the results of TCM syndrome type determination,they were divided into five groups.The number of patients in each group from more to less was deficiency of both yin and yang group(38 cases),yin deficiency and yang-excess type group(30 cases),blood stasis in collaterals group(23 cases),liver fire hyperactivity syndrome group(19 cases)and phlegm-damp syndrome group(18 cases).2.The rank order of blood homocysteine level from high to low for each TCM syndrome type is: phlegm dampness syndrome >Deficiency of both yin and yang > Liver fire hyperactivity syndrome >Deficiency of both yin and yang > blood Stasis syndrome.The results of one-way ANOVA showed that there were significant differences in Hcy levels among different syndrome types.3.The duration of hypertension in TCM syndrome groups from high to low is: yin-yang deficiency syndrome group> Yin deficiency yang hyperactivity syndrome group > phlegm dampness syndrome group > blood stasis syndrome group > liver fire hyperactivity syndrome group.Multiple comparisons among the groups,except for the P value of hypertension duration between syndrome type of hyperactivity of yang due to yin-deficiency and phlegm dampness hyperactivity syndrome group was greater than 0.05,the P values of other groups were less than 0.05,indicating that there was no significant difference in the duration of hypertension between yin-yang deficiency group and syndrome type of hyperactivity of yang due to yin-deficiency,and there was significant difference in the course of hypertension among the other groups.4.Among the patients with H-type hypertension and coronary heart disease,the number of patients with grade 1 hypertension was more than that of patients with grade 2 hypertension and grade 3 hypertension in the blood stasis syndrome group,and the number of patients with grade 2 hypertension was more than that of patients with grade 1 hypertension and grade 3hypertension in the other four groups.Statistical tools were used to compare the hypertension grading in each TCM syndrome group.the results showed that P = 0.767 > 0.05,the difference was not statistically significant.5.The number of males was larger than that of females within each group,and comparisons of the gender composition among different groups showed no statistical significance(P > 0.05).Conclusion:1.In this study,the distribution of TCM syndrome types of H-type hypertension with coronary heart disease has its regularity,and the number of patients with deficiency of both yin and Yang is the largest.2.In this study,the highest level of homocysteine in patients with H-type hypertensi on and coronary heart disease was phlegm dampness syndrome.3.In this study,the duration of hypertension in patients with Yin Yang deficiency syndrome,yin deficiency yang hyperactivity syndrome and phlegm dampness hyperactivity syndrome was longer than that in patients with liver fire hyperactivity syndrome and blood stas is obstructing coll aterals syndrome.