Clinical Study Of Jiawei Xiebai Wendan Decoction In The Treatment Of Children Upper Airway Cough Syndrome (Nasal Origin)

Objective:To observe the clinical effect of Jiawei Xiebai Wendan Decoction in the treatment of children upper airway cough syndrome(nasal origin),and to explore a new idea of "Elimination of pathogens through purgation and diuresis" method in the treatment of children upper airway cough syndrome(nasal origin).Methods:Seventy children with upper airway cough syndrome who met the inclusion criteria were divided into 2 groups by the random number table method: 35 cases in the treatment group and 35 cases in the control group.The treatment group was treated with Jiawei Xiebai Wendan Decoction orally;the control group was treated with Amoxicillin Clavulanate Potassium Dry Suspension orally.The course of treatment was 2 weeks,during which the data related to the two groups of children before and after treatment were recorded.The children were followed up at the end of the course of treatment for 3months and the recurrence rate was recorded.Results:1.After chi-square test and rank sum test,the differences between the two groups were not statistically significant in terms of gender,age and duration of illness(P>0.05)and were comparable.2.Total efficacy analysis: Compared with the total effective rate of the two groups,the total effective rate of the treatment group was 94.11%,which was higher than the 88.23% of the control group,the difference was statistically significant(P<0.05),indicating that the treatment group was superior to the control group.3.Comparison within the group after treatment: The differences between the two groups were statistically significant(P<0.05)when comparing before and after the main symptoms(daytime cough,nighttime cough and nature of coughing sputum),secondary symptoms(nasal congestion,runny nose,nasal itch,postnasal drip of influenza,clear throat and thirst)and the total Chinese medicine evidence score,indicating that the treatment methods of both groups could improve the symptoms of the disease.4.Comparison between groups after treatment: In terms of the primary symptoms,the differences between the two groups were statistically significant(P<0.05)in terms of the nature of daytime cough,nighttime cough and coughing sputum,indicating that the treatment group was more effective than the control group in improving the nature of daytime cough,nighttime cough and coughing sputum;In terms of secondary symptoms,there was a statistically significant difference(P<0.05)when comparing the points of nasal congestion,runny nose,itchy nose and thirst,indicating that the treatment group was better than the control group in improving the symptoms of nasal congestion,runny nose,itchy nose and thirst,while the difference was not statistically significant(P>0.05)when comparing the points of throat clearing and post-nasal drip influenza,indicating that there was no difference in the efficacy of the two groups in improving the symptoms of throat clearing and post-nasal drip influenza.5.Analysis of recurrence: There were 2 cases of recurrence in the treated group and 9 cases in the control group,the difference was statistically significant(P<0.05)and the recurrence rate was significantly lower in the treatment group than in the control group.Conclusions:1.Jiawei Xiebai Wendan Decoction is effective in the treatment of children upper airway cough syndrome(nasal origin),and is superior to Amoxicillin Clavulanate Potassium Dry Suspension.2.Jiawei Xiebai Wendan Decoction is superior to Amoxicillin Clavulanate Potassium Dry Suspension in improving the main symptoms(day cough,night cough,sputum expectoration)and secondary symptoms(nasal congestion,runny nose,nasal itching,thirst)in children.3.Jiawei Xiebai Wendan Decoction is superior to Amoxicillin Clavulanate Potassium Dry Suspension in reducing the recurrence rate of upper airway cough syndrome in children.