Clinical Observation Of Tongdu Tiaoshen Acupuncture Combined With Drugs In The Treatment Of Post-stroke Depression

1.Objective:In this study,to observe the clinical efficacy of Tongdu Tiaoshen Acupuncture combined with Duloxetine Hydrochloride Enteric Capsules in the treatment of post-stroke depression(PSD).Observation of combination of acupuncture with medicine on depression after apoplexy in Hamilton depression rating scale(HAMD-24),improvement of National Institutes of Health Stroke Scale(NIHSS),Daily life activities ability scale(ADL),5-HT content determination of plasma treatment with aspects such as improving is better than single western medicine,for their treatment of PSD is effective and can reflect special advantage of traditional Chinese medicine therapy.2.Methods:The 40 eligible patients diagnosed with PSD were classified into number 1 ~ 40 in sequence,with 20 cases in the control group and 20 cases in the experimental group.Each group patients were corresponding treatment according to the underlying disease,the control group on the basis of conventional treatment to duloxetine hydrochloride enteric capsule treatment,the experimental group in the control group on the basis of tong du adjustable god acupuncture treatment method(using the method of tong du adjustable god acupuncture combined duloxetine enteric capsules),treatment of six times a week,and treatment for 8 weeks,4 weeks for a period of treatment,after treatment with corresponding,4 weekend before treatment and after treatment respectively,observe and record 8 weekend rating scale,the plasma content of 5-HT to evaluate the clinical curative effect and security of the two group.3.Results:3.1.Plasma 5-HT content in both groups:The comparison between the two groups before treatment showing P higher than0.05.After 1 course of treatment and 2 courses of treatment,the comparison between the two groups before and after and the two groups showing that P was lower than 0.05.3.2.Hamilton Depression Scale(HAMD-24)score:Before treatment,the P of the two groups was 0.05,indicating that the two groups were comparable.After 1 course and 2th of treatment,the comparison shows that P was lower than 0.05,suggesting that HAMD-24 score could be reduced in both groups.3.3.National Institutes of Health Stroke Scale(NIHSS)score:Before treatment,the P of the two groups was 0.05,indicating that the two groups were comparable.After 1and2 courses of treatment,the comparison between the two groups before and after treatment shows that P was lower than 0.05.3.4.Barthel(Barthel)score:Before treatment,the P of the two groups was 0.05,indicating that the two groups were comparable.After 1 and 2 courses of treatment,the comparison between the two groups before and after treatment shows that P was lower than 0.05.3.5.Total efficacy of the two groups:The experimental group’s total-rate was higher.The total effective rate of PSD treatment in the two groups was 85% in the experimental group and 75% in the control group,respectively.The comparison of total effective rate was showing that P was lower than 0.05.4.Conclusion :Both groups could reduce HAMD-24,NIHSS score and increase Barthel score and plasma 5-HT content,which had clear efficacy for PSD patients.However,the experimental ’s rate was very higher,indicating that the clinical efficacy of acupuncture and drug combination was superior to drug therapy,with good safety and little side effects,and has certain clinical significance.