Comparison Of Fundus Morphology Between General High Myopia And Pathological Myopia

Objective:To compare the morphology and structure changes of macular area between general high myopia and pathological myopia in adults.And to discuss the fundus morphological changes of high myopia progressing to pathological myopia in clinical.Methods:Forty patients(74 eyes)with high myopia(Age>40,SE<-6.00 D,AL>26mm)were collected.According to the Meta-PM study,the patients with high myopia were divided into two groups: the general high myopia group and the pathological myopia group.The thickness of retina,nerve fiber layer,choroid,sclera in macular ETDRS area and posterior sclera shape were compared between the two groups.Results:In this study,29 eyes were in the general high myopia group and 45 eyes were in the pathological myopia group.There was no statistically significant difference in age between the two groups(P=0.84).There were statistically significant differences in spherical equivalent(SE)、axial length(AL)and best corrected visual acuity(BCVA)between two groups(t=-6.65,t=-5.57,t=6.21,all P<0.01).Compared with general high myopia,retina thickness(RT)and choroid thickness(CT)in pathological myopia were thinner,and the difference was statistically significant(P <0.05).There was no significant difference in nerve fiber layer thickness(RNFLT)、scleral thickness(ST)and posterior sclera shape between the two groups(P>0.05).Conclusion:Compared with high myopia,pathological myopia has higher refraction,longer axial length,worse best corrected visual acuity,also has thinner retinal and choroid thickness.Nerve fiber layer thickness and scleral thickness and posterior sclera shape remain stable.Axial length and choroidal thickness can be used as indicators for clinical progress of high myopia.