Clinical Study Of Suspension Moxibustion Regulating The Acute Inflammatory Response Of Rheumatic Fever Type RA Based On The Theory Of "Heat Syndrome Can Be Moxibustion"

Objective: Through the clinical randomized controlled trial,this subject observed the clinical efficacy of suspended moxibustion combined with basic treatment in the treatment of rheumatic fever type RA,and discussed the advantages of treatment of RA,and further proved the theory that "heat syndrome can be moxibustion" in the clinical aspect.Methods: Eighty patients meeting the inclusion criteria were divided into treatment group and control group.Basic treatment: Oral methotrexate tablets 10 mg,folic acid tablets5 mg after 24 hours,once a week;Treatment group: suspension moxibustion at Ashi point,Dazhui point,bilateral Yinlingquan,Quchi and Zusanli point were used on the basis of basic treatment.Each acupoint was 10 min,once a day,6 days as a cycle,and 4 cycles were treated.Control group: diclofenac sodium sustained-release capsule 50 mg was added to the basic treatment,taken orally,once a day,6 days as a cycle,for 4 cycles.Observation indexes were recorded 1 day before treatment and 1 day after 4 cycles of treatment,and the statistical results of the two groups were analyzed.Results:1.Overall efficacy: The effective rate of the treatment group was 94.73%,and that of the control group was 81.57%.There was a significant difference between the two groups(P<0.05),and the treatment group was significantly better than the control group.2.TCM syndrome score: Difference between the two groups,t=1.759,P=0.083,there was no statistical significance(P>0.05).Within the two groups,there was statistical difference(P<0.001).3.TCM symptom score: Comparison between groups: the improvement degree of joint swelling in the treatment group was better than that in the control group(P<0.05),and there were no significant differences in joint pain,morning stiffness,limited activity,joint fever and thirst(P>0.05).Intra-group comparison: TCM symptoms were improved in both groups(P<0.001).4.VAS score and DAS28 score: Comparison between groups: there was no significant difference in the reduction of VAS score between the two groups(P>0.05),and the reduction of DAS28 score in the treatment group was significantly better than that in the control group.Comparison within groups: VAS score and DAS28 score were decreased in both groups(P<0.05).5.Laboratory indicators: Comparison between groups: the decrease of anti-CCP value in the treatment group was significantly better than that in the control group(P<0.05),but there were no significant differences in the decrease of RF,CRP,ESR and ASO values between the two groups(P>0.05).Intra-group comparison: the laboratory indicators were decreased(P<0.05).6.Safety: Adverse reactions occurred in both groups during treatment,both of which were mild,and there was no statistical difference in adverse reactions between the two groups(P>0.05).Conclusion:1.Both suspension moxibustion combined with basic treatment and diclofenac sodium sustained-release capsule combined with basic treatment are effective for rheumatic fever type RA,but suspension moxibustion combined with basic treatment is more effective.2.Both suspension moxibustion combined with basic treatment and diclofenac sodium sustained-release capsule combined with basic treatment can improve TCM syndrome,TCM symptoms,pain degree and joint disease activity in RA patients with rheumatic fever type.Comparatively speaking,suspension moxibustion combined with basic treatment is more obvious in improving the degree of joint swelling and joint disease activity.3.Both suspension moxibustion combined with basic treatment and diclofenac sodium sustained release capsule combined with basic treatment can reduce the RF,anti-CCP,CRP,ESR,ASO indexes in patients with rheumatic fever rheumatism type RA,but suspension moxibustion combined with basic treatment is more obvious in reducing the anti-CCP indexes.