Objective:1.To observe the distribution characteristics of TCM syndromes in the pre-diabetic population in Qilihe District,Lanzhou City,and provide a reference for the establishment of the TCM syndrome differentiation system for the pre-diabetic population in Lanzhou.2.To study the TCM syndrome types and age,gender,ethnicity,education level,smoking history,drinking history,family history of diabetes,blood lipids(TG,TC,HDL-C,LDL-C),body mass index in the pre-diabetic population in Qilihe District,Lanzhou City The correlation between(BMI),waist circumference,hip circumference,waist-to-hip ratio(WHR),etc.,provides scientific basis for the pre-diabetic population in Lanzhou to develop a healthy lifestyle with traditional Chinese medicine characteristics and intervention treatment of traditional Chinese medicine to prevent and delay type 2 diabetes happened.Methods:This project adopted a cross-sectional research method and used on-site questionnaire surveys to systematically collect multiple community service centers in Qilihe District,Lanzhou City,Gansu province,the physical examination center,and the endocrinology outpatient clinics of Qilihe District,Lanzhou City,Gansu province from October 2019 to December 2020.Basic information(age,gender,ethnicity,educational level,personal history,family history of diabetes,history of hypertension,etc.)and TCM symptoms,tongue and pulse information,etc.of pre-diabetes patients in the inpatient department,according to the syndrome criteria for TCM syndrome differentiation,And the age,gender,ethnicity,education level,smoking history,drinking history,history of hypertension,family history of diabetes,body mass index(BMI),waist circumference,hip circumference,waist-to-hip ratio(WHR),blood lipid(TG,TC,HDL-C,LDL-C)and other data using SPSS25.0 statistical software for statistical analysis to observe the distribution characteristics of TCM syndromes in the pre-diabetic population.Results:1.Among the 505 pre-diabetic populations included in this study,gender:278males(55.0%),227 females(45.0%),the ratio of males to females was 1.22:1;ethnicity:359cases of Han(71.1%),Hui nationality 146 cases(28.9%);age:the youngest age is 18 years old,the oldest age is 70 years old,the distribution of the largest number is 40-59 years old;education level:the number of people with primary school and below education level is the largest,a total of 261 cases(51.7%);personal history:95 cases(18.8%)with a history of smoking,135 cases(26.7%)with a history of drinking;family history of diabetes:270 cases(53.5%)with a family history of diabetes;combined with hypertension There are 195 cases(38.6%)of patients with BMI and waist circumference:a total of 304 cases of overweight and obesity(60.2%),313 cases of central obesity(62.0%).2.In this study,the TCM syndromes of pre-diabetes were mainly divided into 139 cases of Qi and Yin deficiency syndrome(27.6%),97 cases of spleen and stomach stagnation syndrome(19.2%),91 cases of liver and stomach stagnation-heat syndrome(18.0%),liver There were 90 cases of depression and spleen deficiency syndrome(17.8%),and 88 cases(17.4%)of yang deficiency and cold dampness syndrome.Among them,the syndrome of deficiency of both qi and yin and spleen and stomach stagnation were the most common.3.There is no statistically significant difference in gender and age composition of different syndrome types(P>0.05).4.The prevalence of hypertension of various syndromes: the prevalence of hypertension of different syndromes was not statistically different(P>0.05).5.Comparison of BMI,waist circumference,hip circumference,waist-hip ratio(WHR)of each syndrome type: BMI,waist circumference,hip circumference,and WHR of the spleen and stomach stagnation syndrome group are higher than the other four groups,among which BMI,hip circumference and others The difference between the four groups was statistically significant(P<0.05),and the other four syndrome types had no statistical difference in BMI,waist circumference,hip circumference,and WHR(P>0.05).6.Comparison of TG of various syndrome types:TG levels of various syndrome types,spleen and stomach stagnation syndrome>Yang deficiency,cold dampness syndrome>Qi and Yin deficiency syndrome>liver and stomach stagnation heat syndrome>liver and stomach stagnation heat syndrome.Among them,Qi and Yin deficiency syndrome group and liver depression and spleen deficiency syndrome group,spleen and stomach stagnation syndrome group and liver depression and spleen deficiency syndrome group,liver and stomach stagnation heat syndrome group,liver depression and spleen deficiency syndrome group and Yang deficiency cold dampness syndrome group,liver and stomach stagnation heat syndrome group There was a statistically significant difference between the spleen and stomach stagnation syndrome group,the Yang deficiency cold-dampness syndrome group,the Yang deficiency cold-dampness syndrome group,the liver stagnation and spleen deficiency syndrome group,and the liver and stomach stagnation-heat syndrome group(p<0.05).7.Comparison of TC,LDL-C,HDL-C of various syndrome types:There was no statistically significant difference in TC,LDL-C,HDL-C of different syndrome types(p>0.05).Conclusion:1.Frequent symptoms and tongue pulses in this study:fatigue,upset,irritability,gastric discomfort,dull complexion,bitter mouth,five upset fever,obesity,red tongue,thin white coating,strong pulse,etc.suggesting diabetes The early TCM syndrome elements may be deficiency,excess,heat,qi,etc.The disease is located in the spleen,liver,and stomach,and the basic syndromes may be qi deficiency,yin deficiency,qi stagnation,damp-heat,etc.In clinical practice,patients with pre-diabetes should be treated according to the disease nature and location,and the correct prescription should be selected to improve the clinical efficacy of traditional Chinese medicine.2.In this study,505 patients with pre-diabetes were mainly divided into five syndrome types: Qi and Yin deficiency,spleen and stomach stagnation syndrome,liver and stomach stagnation and heat syndrome,liver depression and spleen deficiency syndrome,and Yang deficiency and cold dampness syndrome.Based on the evidence of evidence-based medicine,the expert team will conduct research in other areas of Lanzhou City,Tianshui City,and Linxia prefecture in other areas of Lanzhou City,Tianshui City,and Linxia prefecture.The research on TCM syndrome differentiation of pre-diabetes population will further formulate the "Clinical Diagnosis and Treatment Standards of pre-diabetes TCM in Gansu province" to improve the level of TCM prevention and treatment of diabetes in our province.3.The age of onset of prediabetes patients is mainly concentrated after the age of 40.people who are ≥ 40 years old,have a family history of diabetes,are overweight or obese,central obesity,and dyslipidemia can be regarded as high-risk groups for prediabetes.Clinically,we should encourage this part of the population to start screening for diabetes as soon as possible,and provide healthy lifestyles such as reasonable diet,weight control,and traditional Chinese medicine intervention treatment to reduce the incidence of diabetes in our province and promote the economic development of traditional Chinese medicine in our province.4.The average levels of BMI,waist circumference,hip circumference,and TG of pre-diabetes spleen and stomach stagnation syndrome are higher than those of other syndrome types,and the differences in BMI and TG of different syndrome types are statistically significant.Therefore,BMI and TG can be used as pre-diabetes spleen and stomach stagnation.The reference index of micro-diagnosis of syndrome.In clinical treatment of pre-diabetes through the combination of disease and syndrome,it is necessary to pay attention to the patient symptom improvement,and also to regard the changes in micro-syndrome differentiation indicators as the criterion for judging the efficacy of TCM.Improve the recognition of the curative effect of Chinese medicine. |