The Clinical Research Of The Treatment Of Insomnia Of Liver Depression And Spleen Deficiency With Self-Made Anshen Decoction

Objective:The subject aims at evaluating the effectiveness and safety of Self-made Anshen Decoction,in order to relieve the pain of patients.Methods:This study was conducted from January 2020 to December 2020 in Xiamen Hospital of Traditional Chinese Medicine.There were 70 patients with insomnia who accorded with the inclusion criteria.The subject was randomly divided into the observation group and the control group by using SPSS23.0,the control group(35 patients)was offered “Alprazolam Tablets”,and the insomniac in the observation group(35patients)was extrally provided with“Self-made Anshen Decoction” on the basis of the control group.The treatment for both two groups was four weeks with 1 month of follow-up.Curative effectivenes of “Self-made Anshen Decoction” were evaluated on the basis of changes in clinical symptom before and after.This article discusses the theoretical basis of “self-made Anshen Decoction” in the treatment of insomnia caused by the liver staganation and spleen deficiency,observed and wrote whether the subject had obvious adverse reactions,evaluated the efficacy and safety of“Self-made Anshen Decoction”.Results:1.A total of 70 patients were included in this clinical study,68 patients completed clinical observation,each group fell off 1 case,the total shedding rate was 2.86%。2.Before treatment,there was no significant difference in the score of sex,age,PSQI scale and TCM syndrome scores between the two groups(P>0.05).3.After 4 weeks of treatment,compared with the PSQI score of the two groups,the total effective rate of the observation group was 91.18%,and the total effective rate of the control group was 70.59%,with statistical difference between the two groups(P<0.05).After 4 weeks of treatment,the total effective rate of the observation group and the control group was91.18% and 44.12%,respectively,with statistical difference(P<0.05).4.After 4 weeks of treatment,the PSQI scale score and TCM syndrome score of the two groups were improved(P<0.05).Compared with the control group,the observation group had advantages in improving Sleep Efficiency,Sleep disturbances and Daytime Function(P<0.05).Compared with the control group,the observation group had advantages in improving diarrhea and anorexia,bowel sounds and farting,abdominal pain,abdominal pain reduction(P<0.05).5.The PSQI score of the control group declined,the difference was statistically significant(P<0.05).The TCM syndrome score of the control group increased,the difference was statistically significant(P<0.05).Groups comparison also had different(P<0.05).The total effective rate of PSQI in the observation group was better than that in the control group(P<0.05).6.No adverse reactions were found in the two groups during the period of medication.There was no obvious abnormality in the blood routine,liver function,renal function before and after the treatment.Conclusions:1.The clinical effect of “Self-made Anshen Decoction” Combined with “Alprazolam Tablets” in the treatment of insomnia of liver depression and spleen deficiency type was effective.Compared with “Alprazolam Tablets” alone,“Self-made Anshen Decoction”group had more advantages in reducing PSQI score,TCM syndrome score and improving overall clinical efficacy.2.According to the follow-up results,the sleep status and TCM symptoms of the“Self-made Anshen Decoction” group were still better than those of the “Alprazolam Tablets”group one month after drug withdrawal.