Clinical Study On Treatment Of Chronic Insomnia With Liver Depression And Spleen Deficiency By Jianpi Shugan Anshen Decoction

In this study,we investigated the clinical efficacy of esparaZol tablets plus Jianpi Shugan Anshen Recipe and estaZolam tablets in the treatment of chronic insomnia patients with liver stagnation and spleen deficiency,and explored the clinical significance of Jianpi Shugan Anshen Recipe.Clinical treatment of chronic spleen deficiency and chronic insomnia provides ideas.According to the chronic insomnia and the "Guidelines for Clinical Research of New Drugs in Traditional Chinese Medicine",the diagnostic criteria for liver stagnation and spleen deficiency syndrome were included in the clinic of ShijiaZhuang City Hospital from October 2016 to November 2018.72 outpatients in the laboratory were randomly divided into control group and treatment group,36 cases in each group.The control group was given estaZolam tablets.The treatment group was treated with Jianpi Shugan Anshen Recipe on the basis of the control group.The two groups were treated for 4 weeks.Pittsburgh sleep quality index scale(PSQI),liver stagnation and spleen deficiency syndrome quantitative score table were used to observe the curative effect.The data were analyZed by SPSS22.0 statistical analysis.During the clinical observation period,there were 3 cases of shedding,the shedding rate was 4.2%,the shedding rate was ≤10%,1 case was the treatment group,2 cases were the control group,and 69 cases were statistically analyZed.No adverse events occurred.Statistical results There were no significant differences in gender,age,duration,Hamilton scale,SPIEGEL scale score,and TCM syndrome quantitative scores and PSQI scores before treatment(P>0.05),which were comparable;91.4% in theefficiency treatment group and 73.5% in the control group,there was a statistically significant difference(P<0.01).The treatment group was superior to the control group in the TCM syndrome score group after treatment,in total score,sleep condition,emotion Depression,food intake,phlegm and pain,complaints,abdominal pain,bloating,abdominal distension scores were statistically different(P<0.05).The treatment group was compared with TCM syndrome scores before and after treatment.Statistical difference(P<0.01),the comparison of sleep and bloating scores in TCM syndromes before and after treatment in the control group,after treatment was better than before treatment,there was statistical difference(P<0.05),sputum pain,abdominal pain and diarrhea,There were no statistically significant differences in the scores of depression,loss of food,and depression(P>0.05).The comparison between the two groups after treatment was compared with the control group,which was superior to the control group in total score,sleep time,and sleep efficiency.The rates,daytime dysfunction,sleep time,sleep quality,and sleep disorder scores were statistically different(P<0.05).The scores of PSQI before and after treatment in the treatment group and the control group were better than those before treatment.(P<0.05).In the end,it is concluded that:(1)Jianpi Shugan Anshen Recipe combined with estaZolam tablets and estaZolam tablets alone can improve the insomnia of patients with chronic insomnia,but Jianpi Shugan Anshen Recipe combined with estaZolam tablets The efficacy of insomnia in patients is better than that of estaZolam alone;(2)taking spleen and soothing liver and nerve combined with estaZolam tablets is superior to estaZolam alone in treating TCM syndromes of chronic insomnia with liver stagnation and spleen deficiency;(3)from the heart and liver spleen to treat liver stagnation and spleen deficiency type chronic insomnia can improve patients with insomnia and TCM syndromes,has a certain clinical promotion value.