Retrospective Study On The Treatment Of Ischemic Leukoencephalopathy With Traditional Chinese Medicine

The first part of this article reviews the modern medical research of ischemic leukoencephalopathy,and combs the understanding and exploration of traditional Chinese medicine on the physiological functions of the brain and the names,pathogenesis and treatment of Chinese medicine related to leukoencephalopathy.The clinical research part is a retrospective study of clinically diagnosed ischemic leukoencephalopathy.167 cases with treatment time of 1 month,2 months,and 3 months were screened out,and 0,1,2,and 3 cases were recorded.713 visits a month.Research purposes:(1)To study the comorbidities of ischemic leukoencephalopathy,and to analyze the relationship between possible risk factors and diseases;(2)To evaluate the efficacy of traditional Chinese medicine in the treatment of ischemic leukoencephalopathy and the efficacy of test indicators;(3)Summarize Professor Huang Shijing’s core prescriptions for the treatment of this disease and clinical medication,explore the diagnosis and syndrome types of ischemic leukoencephalopathy in Chinese medicine,and compare the similarities and differences of medications under different Chinese medicine diagnoses.Research method:Screening the included cases,compiling the case report form,extracting the research data,establishing the Excel database and performing frequency and frequency statistics,using spss20.0 to calculate the mean ± standard deviation and draw the PP diagram to test whether it conforms to the normal distribution,Apply Levene’s test to test the homogeneity of variance,and finally use the T test to compare the two sets of data,and plot the results into a chart.Research results:(1)According to the frequency of occurrence,the top ten comorbidities were hypertension,hyperlipidemia,type 2 diabetes,arteriosclerosis,lacunar infarction,cerebral infarction,depression,and coronary artery Atherosclerotic heart disease,osteoporosis,insomnia.(2)The frequency of main symptoms of ischemic leukoencephalopathy in descending order are memory loss,sleep disturbance(including difficulty falling asleep,light sleep and easy awakening,difficulty falling asleep after waking,etc.),head discomfort(including dizziness,dizziness,head Dizziness),impatience,irritability,depression,lack of breath,abnormal urination,poor executive ability(including slow response,improper response),emotional apathy(including loss of interest or poor initiative)and lower limb dysfunction,except for emotional apathy,The other main symptoms have all improved well.(3)In terms of inspection indicators:the differences in blood pressure and homocysteine after intervention were statistically significant.Among them,the systolic blood pressure was reduced by 8.06 mmHg,9.61 mmHg,and 11.03 mmHg,respectively,and the diastolic blood pressure was average Decrease 2.77 mmHg,7.63mmHg,7.01mmHg.There were no statistically significant differences in blood glucose,triglycerides,total cholesterol,high-density lipoprotein,and low-density lipoprotein.(4)The most commonly used traditional Chinese medicines for the treatment of ischemic leukoencephalopathy are Polygala,Poria,Astragalus,Pueraria lobata,Shichangpu,Dilong,Polygonatum,Sour Ziziphus,Panax notoginseng and Tianma.The core prescription consists of Polygala,Poria,Shichangpu,Pueraria,and Safflower.(5)Common TCM diagnoses of ischemic leukoencephalopathy are vertigo,amnesia,insomnia,edema,diabetic,stroke,tinnitus,palpitations,arthralgia,headache,tremor;common TCM Syndrome types are liver and kidney deficiency,qi and blood deficiency,phlegm and blood stasis,qi stagnation and phlegm stagnation,qi and yin injury,kidney essence deficiency,and spleen-yang deficiency.Research conclusions:(1)Traditional Chinese medicine intervention can effectively improve the clinical symptoms of patients with ischemic leukoencephalopathy;(2)Chinese medicine can effectively control the systolic and diastolic blood pressure of patients with ischemic leukoencephalopathy,and can reduce the serum homocysteine level;(3)The core prescriptions for the treatment of ischemic leukoencephalopathy are Polygala,Poria,Shichangpu,Pueraria lobata,safflower,mainly to soothe the nerves,nourish the mind,resuscitate and reduce phlegm,and can be considered as the basic treatment of this disease.