| ObjectivesTo construct auricular-plaster therapy intervention program for cancer related fatigue of postoperative breast cancer patients undergoing chemotherapy based on syndrome differentiation,and then to explore the effect of auricular-plaster therapy on cancer related fatigue and the quality of life of postoperative breast cancer patients undergoing chemotherapy,so as to provide basis for clinical nursing intervention.MethodsThe subjects of study were 76 cases of breast cancer patients with first postoperative chemotherapy in a tertiary hospital of Hunan Province from February 2019 to January 2020.According to random number table.,the Breast Department(Inpatient Ward No.16)was randomly set as the experimental group and the Breast Department(Inpatient Ward No.15)as the control group.The convenience sampling method was used to collect38 patients in the experimental group and 38 patients in the control group.Subjects in both groups were provided with routine nursing,On the basis of routine nursing,acupoint selection based on syndrome differentiation was performed for subjects in the experimental group according to five different syndrome types,with the application of four chemotherapy cycles with vaccaria seed auricular-plaster for intervention.The five syndrome types were described as follows:(1)Syndrome of stagnation of liver Qi: Auricular point of liver,Auricular point of spleen,and Endocrine point;(2)Syndrome of deficiency of spleen Qi: Auricular point of spleen,Auricular point of stomach,and Shenmen point;(3)Syndrome of deficiency of Qi and blood: Shenmen point,Subcortical point,and Sympathetic point;(4)Syndrome of kidney-yang deficiency: Auricular point of kidney,Auricular point of spleen,and Shenmen point;(5)Syndrome of deficiency of heart Qi: Auricular point of heart,Auricular point of breast,and Sympathetic point.All subjects completed surveys of general data,Brief Fatigue Inventory(BFI)and Functional Assessment of Cancer Therapy-Breast(FACT-B)on the day of admission(T0).Meanwhile,repeated evaluation using BFI and FACT-B was conducted at the time of the first chemotherapy(T1),the second chemotherapy(T2),the third chemotherapy(T3)and the fourth chemotherapy(T4).IBM SPSS 22.0 software was used to analyze the data,Chi-square test was used to compare the composition ratio of two groups,rank sum test was used to test the grade data of two groups,and two independent samples t-test was used to compare the mean values of two groups.The repeated measurement ANOVA was performed to compare the outcome indexes of the two groups at 5 time points(T0,T1,T2,T3,and T4)before and after intervention,the test level α =0.05.Results1.Comparison of results between groups before intervention(1)There was no significant difference in demographic data and disease characteristics between the two groups(P>0.05).(2)Before the intervention,patients in the two groups had moderately high levels of cancer-related fatigue.The score of BFI was(5.96±0.87)points and(5.69±0.84)points in the control group and the experimental group.No significant difference was observed in the scores of cancer related fatigue between the control group and the experimental group(P>0.05).There was no significant difference in mild fatigue,moderate fatigue and severe fatigue between the two groups(P>0.05).(3)The quality of life score was(99.28±6.01)points and(99.08±9.28)points in the control group and the experimental group.No significant difference was observed in the scores of quality of life between the control group and the experimental group(P>0.05).2.Comparison of results between groups after intervention(1)Cancer related fatigue score: It was(6.25±0.80)points,(6.88±0.87)points,(7.29±0.70)points,and(7.80±0.56)points at T1,T2,T3,and T4 in the control group,respectively;while the score was(5.14±0.75)points,(3.96±0.85)points,(3.43±0.73)points,and(2.89±0.78)points in the experimental group,respectively.Comparison between groups showed that there were significant differences in both the intervention main effect(P<0.05)and time main effect(P<0.05)of fatigue scores between the two groups.The score of experimental group is lower than the control group.With the passage of time,the scores of cancer-induced fatigue in the experimental group decreased gradually,while those in the control group increased gradually.Besides,there was interaction between intervention factor and time factor within experimental group(P<0.05).(2)Quality of life score: It was(84.92±5.35)points,(80.19±4.83)points,(80.58±5.36)points,and(77.94±5.64)points at T1,T2,T3,and T4 in the control group,respectively;while the score was(92.47±9.04)points,(93.61±5.61)points,(94.39±6.06)points,and(97.64±5.71)points in the experimental group,respectively.The results revealed that there were significant differences in the quality of life and intervention main effect of each dimension between the two groups(P<0.05),as well as significant differences in time main effect(P<0.05).The quality of life of patients in the control group decreased over time,while the quality of life of patients in the experimental group first decreased over time and gradually increased from the second chemotherapy.In addition,there was interaction between intervention factor and time factor within experimental group(P<0.05).ConclusionsPostoperative breast cancer patients undergoing chemotherapy have moderately elevated cancer related fatigue.The application of auricular-plaster therapy through nursing based on syndrome differentiation can reduce cancer related fatigue and improve the quality of life in patients of postoperative breast cancer undergoing chemotherapy. |
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