The Study Of Curative Effect Of Jiawei Shengmai San Powder On Deficiency Of Qi And Yin After Thyroid Cancer Operation

ObjectiveThe main purpose of this clinical study was to observe the effect of Jiawei Shengmai San on the clinical symptoms and thyroid function of patients with Qi and Yin deficiency syndrome after thyroid cancer surgery,and to understand the curative effect of Jiawei Shengmai San on patients with thyroid cancer who neglected Qi and Yin deficiency.MethodsUsing a prospective randomized controlled study method,62 patients with postoperative syndrome of thyroid cancer who met the inclusion criteria were randomly divided into a control group and an observation group with 31 cases in each group,combined with a random number table.The control group was treated with Youjiale,and the observation group was treated with Youjiale combined with Jiawei Shengmai San.The course of treatment was 4 weeks.The dose of Youjiale in the two groups was adjusted according to the patient’s thyroid function level.Observe the changes of the clinical symptoms of traditional Chinese medicine and the thyroid level of the two groups of patients.Results1.In the aspect of Karnofsky score:the two groups before treatment Karnofsky score no statistical significance(P>0.05),control group and observation group Karnofsky score after treatment than before treatment were increased,the difference had statistical significance(P<0.05),and the observation group increase Karnofsky score higher than control group(P<0.05),the two groups of patients after treatment was to improve the life quality,improve performance and observation group is better than the control group.2.Effectives of TCM syndromes:after treatment,the total effective rate of the control group was 77.42%,and the total effective rate of the observation group was 100%,and the difference in effective rate between the two groups was statistically significant(P<0.05).3.In terms of TCM syndrome score,after treatment,the total TCM syndrome score in two groups decreased compared with before treatment,and the difference was statistically significant(P<0.05).The decrease in the total TCM syndrome score in the observation group was significantly greater than that in the control group(P<0.05),and there was a significant difference in the total scores between the two groups(P<0.05).According to single syndrome analysis of traditional Chinese medicine,compared with before treatment,fatigue,shortness of breath and lazy speech,dryness of mouth and throat,dysphoria in chestpalms-soles,irritability,insomnia and dreams,spontaneous sweating and night sweating,waist and knee pain and softness were all improved in both groups after treatment,with significant differences(P<0.05).Compared with the control group,the observation group had statistically significant differences in fatigue,shortness of breath and lazy speech,dryness of mouth and throat,dysphoria in chestpalms-soles,irritability,insomnia and dreams,spontaneous sweating and night sweating,constipation after treatment(P<0.05),and the improvement of the above symptoms was better than that of the control group.There was no significant difference between the control group and the observation group in lumbar and knee pain and softenness after treatment(P>0.05).After treatment,the difference between the two groups was statistically significant in shortness of breath and lazy speech,dryness of mouth and throat,irritability,spontaneous sweating,night sweating and constipation(P<0.05).In general,the symptoms of shortness of breath and lazy speech,dry mouth and throat,irritability,spontaneous sweating,night sweating and constipation were significantly improved in the two groups,and the improvement in the observation group was better than that in the control group.4.In terms of thyroid hormone,compared with before treatment,there were statistically significant differences in FT3,FT4 and TSH between the two groups after treatment(P<0.01).After treatment,there was no significant difference in FT3,FT4 and TSH between the control group and the observation group(P>0.05).5.In terms of safety:there were no adverse reactions such as nausea before and after treatment in patients of the two groups,and no obvious abnormalities in vital signs,liver and kidney functions after treatment.Conclusion1.Jiawei Shengmai Powder is safe and reasonable in the research process.2.Jiawei Shengmai Powder has a certain effect on the syndrome of deficiency of both Qi and Yin after thyroid cancer surgery,and can improve patients’ clinical discomfort symptoms such as fatigue,shortness of breath,lazy speech,palpitation,insomnia and dreams,spontaneous sweating and night sweating to a certain extent.3.Jiawei Shengmai San has no significant effect on thyroid function level and does not affect the postoperative TSH inhibition therapy of patients.