Hormone-dependent dermatitis is caused by the long-term use of glucocorticoidcontaining preparations,which temporarily improves the skin disorder.Once the use of such products is stopped,the original skin disease will recur or even worsen,resulting in withdrawal symptoms and forcing the patient to continue using the product,thus creating a kind of "dependence" on hormones.If it occurs on the face,it is called facial hormone dependent dermatitis.In recent years,with the widespread use of glucocorticoids,the incidence of this disease has increased year by year and has become a common disease in dermatology,but the clinical treatment effect is not satisfactory.The recurrence of symptoms seriously affects the quality of life and work of patients.In recent years,with the in-depth research of Chinese medicine on skin diseases,more clinical treatment ideas have been developed for the treatment of such diseases.ObjectiveA randomized controlled trial was conducted to observe the clinical efficacy of pricking and cupping in the treatment of wind-heat skin type facial hormone-dependent dermatitis,thus providing a basis for the clinical treatment of facial hormone-dependent dermatitis.MethodsA total of 66 patients who met the diagnosis of wind-heat facial hormone-dependent dermatitis were included in this study and were randomly divided into 33 cases each in the treatment group and the control group.The treatment group was treated with pricking and cupping therapy,and the control group was treated with tacrolimus ointment.Both groups received oral loratadine tablets and topical cold spray therapy.The cupping therapy was performed every 3 days;and tacrolimus ointment once in the morning and once in the evening;loratadine tablets were administered orally at 10 mg once a day;cold spray therapy was administered 1 time every other day.Both groups were treated for 4 weeks for a total of 1 course of treatment.With reference to the relevant literature in recent years,the criteria of symptom score and improvement of dermatological quality of life index(DLQI)were formulated as indicators for determining the efficacy,and the changes of each index score before treatment,at the second week and the fourth week of treatment,as well as the recurrence rate 1 month after the end of treatment were observed and recorded for statistical analysis to determine the clinical efficacy,recurrence rate and quality of life of the two treatment methods.ResultsAfter the treatment,all clinical observation indexes of patients in both groups improved compared with those before treatment(P<0.05),indicating that both treatments were effective in the treatment of wind-heat guest skin type facial hormone-dependent dermatitis.The total effective rates of the treatment group and the control group were 96.77%and 81.25%,respectively,and the differences were not statistically significant(P>0.05).However,the efficacy of the treatment group was better than that of the control group in improving the three aspects of burning,itching and capillary dilation,which was statistically significant(P<0.05);the efficacy of the control group was better than that of the treatment group in improving erythema,which was statistically significant(P<0.05);the difference was not statistically significant in the treatment of acne-like lesions(P>0.05).Comparing the quality of life scores of the two groups,both groups were able to improve the quality of life of patients,but the efficacy of the treatment group was better(P<0.05).The recurrence rate was 6.67%in the treatment group and 30.77%in the control group when comparing the recurrence rate after 1 month of treatment,with statistically significant differences(P<0.05).ConclusionBoth pricking and cupping therapy and topical tacrolimus ointment therapy are effective in the treatment of wind-heat guest skin type facial hormone-dependent dermatitis,but pricking and cupping therapy is more effective,lower recurrence rate,less side effects,and could significantly improve the quality of life of patients,and the treatment cost is low,which is worthy of further clinical promotion. |