Clinical Observation On Huodi Zhuanggu Decoction In Treating Osteoporosis Of Kidney Deficiency And Blood Stasis Type

Objective: Observe the clinical efficacy of Huodi Zhuanggu decoction in the treatment of osteoporosis due to renal failure and blood stasis,review its mechanism,and determine its protection to provide treatment ideas and references.Methods: 70 osteoporosis patients were treated at the Weifang Traditional Chinese Medicine Hospital’s outpatient clinic and endocrinology department from August 2019 to October 2020.All cases met Western medicine diagnostic criteria for osteoporosis and TCM diagnosis criteria for renal osteoporosis and blood stasis syndrome.All patients were randomly assigned to one of two groups: supervision(n = 35)or care(n = 35).Both groups of patients received the same basic treatment for oral calchi D and Alfa D3 capsules.Xianlinggubao capsules were administered to the control group and Huodi Zhuanggu decoction was administered to the treatment on this basis.The clinical effectiveness of the two groups was measured after three courses of treatment,using the TCM symptom score,bone pain score,bone mineral density,bone metabolism biochemical index,and safety index being measured before and after treatment.The related data was processed and analyzed using SPSS21.0 software.Results:(1)The total clinical effective rate of the treatment group was79.41%,while that of the control group was 69.70%.There was no noteworthy distinction between the two bunches(P>0.05),and the clinical impact was the same.(2)After treatment,the Chinese pharmaceutical prove focuses and bone torment focuses in both bunches made strides essentially(P<0.01),and the advancement within the treatment bunch was better than that within the control gather(P<0.05).(3)The biochemical records of bone digestion system and bone thickness made strides in both bunches after treatment(P<0.05),and the contrast between the two bunches was not factually critical(P>0.05),and the adequacy of progressing bone digestion system and bone thickness was the same in both bunches.(4)No noteworthy changes in security records happened in both bunches amid clinical perception(P>0.05),and no unfavorably susceptible or genuine unfavorable responses happened.Conclusion: Huodi Zhuanggu decoction can altogether progress the clinical side effects of osteoporosis patients with kidney lack and blood stasis,soothe bone torment,increment bone mineral thickness and control bone digestion system,secure and successful,commendable of assist consider.Compared with Xianlinggubao capsule,Huodi Zhuanggu decoction is more viable than Xianlinggubao capsule in moving forward TCM side effects and diminishing bone torment,but there’s no significant distinction within the change of bone mineral thickness,the change of bone digestion system and the generally clinical impact.