Objective: To observe and evaluate the clinical efficacy of hemorrhoid disinfecting lotion fumigation and sitting bath in the treatment of thrombotic external hemorrhoids,and to provide the basis for clinical application.Methods: A total of 60 patients who met the inclusion criteria and would be treated in the outpatient and inpatient department of gastroenteroanal surgery of the First Affiliated Hospital of Guangxi University of Chinese Medicine from January 2020 to January 2021 were randomly divided into the treatment group and the control group(30 patients in each group),with 1 case falling out in the treatment group and 2 cases falling out in the control group.Patients in the treatment group were given hemorrhoid dissolving lotion fumigation bath,and patients in the control group were given 1:5000 potassium permanganate fumigation bath.Two groups of patients were treated with the same method and procedure,and sat bath once morning and evening,for a course of 7 days.Anal pain,anal edge edema degree and local skin color changes were observed before treatment and on the 3rd and 7th day of treatment in the two groups,and graded quantitative scores were conducted.SPSS20.0 software was used to conduct statistical analysis on the obtained data,and the differences in various indicators between the two groups were compared to evaluate the clinical efficacy of hemorrhoid disinfective lotion.Results: In this study,there was 1 case of abscission in the treatment group and 2 cases in the control group.A total of 57 patients finally completed this study.No adverse events were observed in all patients during the study.The differences in gender(male/female:13/16 VS 14/14,P=1.000),age(41.103±1.988 VS 43.393±2.178,P=0.440)and course of disease(2.655±0.218 VS 2.679±0.219,P=0.901)between the treatment group and the control group were not statistically significant and were comparable.Before treatment,anal pain score(5.828±0.217 VS 5.857±0.240,P=0.927),anal edge edema score(4.552±0.241 VS 4.286±0.267,P=0.481)and local skin color score(4.138±0.242 VS 3.857±0.228,P=0.398)were compared between the two groups,showing no statistical difference and comparable.Comparison of efficacy between the two groups after treatment: 1.Pain score: in the treatment group,the pain score of the first course after treatment was significantly reduced compared with that before treatment(5.828±0.217 VS2.276±0.243,P < 0.05);In the control group,there was a decrease after 1course of treatment compared with before treatment(5.857±0.240 VS3.143±0.234,P < 0.05).On day 3 of treatment,the treatment group was lower than the control group(3.345±0.234 VS 4.071±0.241,P < 0.05).On day 7 of treatment,the treatment group was lower than the control group(2.276±0.243 VS 3.143±0.234,P < 0.05).2.Degree of anal edema: in the treatment group,after 1 course of treatment,the score of anal edema was significantly lower than that before treatment(4.552±0.241 VS 1.103±0.291,P < 0.05).In the control group,the perianal edema score after 1 course of treatment was lower than that before treatment(4.286±0.267 VS 2.071±0.333,P < 0.05).On day 3of treatment,the treatment group was lower than the control group(2.483±0.256 VS 3.286±0.276,P < 0.05).On day 7 of treatment,the treatment group was lower than the control group(1.103±0.291 VS 2.071±0.333,P<0.05).3.Local skin color score: in the treatment group,after 1 course of treatment,it was significantly decreased compared with before treatment(4.138±0.242 VS 1.379±0.299,P<0.05).In the control group,the scores after 1course of treatment were lower than those before treatment(3.857±0.228 VS2.357±0.326,P<0.05).On day 3 of treatment,the comparison between treatment group and control group was(2.414±0.304 VS 3.143±0.261,P<0.05).On day 7 of treatment,the treatment group was compared with the control group(1.379±0.299 VS 2.357±0.326,P<0.05).4.Comparison of overall efficacy: the total effective rate of the treatment group was 96.552%,and the total effective rate of the control group was 89.286%.Compared with the two groups,the treatment group was higher than the control group,with statistical difference(P < 0.05).Conclusion(s): Hemorrhoid disinfecting lotion fumigation and sitting bath can relieve anal pain symptoms of patients with thrombotic external hemorrhoids,relieve anal edema,improve local skin color,and have no adverse events.It is a safe,effective,simple and convenient method for the treatment of thrombotic external hemorrhoids,and worthy of clinical promotion. |