Effect Of Modified Sanzi Decoction On The Effect Of Phlegm-stasis Lung Type AECOPD And Inflammatory Indexes

ObjectiveTo observe the clinical effect of modified sanzi decoction combined with conventional western medicine in the treatment of chronic obstructive pulmonary disease(AECOPD)with Acute exacerbation of phlegm and stasis.This test from the White blood cell count,White blood cell,the WBC),calcitonin(Procalcitonin,PCT),TCM syndrome integral,6 minutes walking distance(6 minute walk test,6 MWT),chronic obstructive pulmonary disease ass essment test(COPD assessment test,CAT),clinical curative effect evaluation,in order to in vestigate the third internal and flavored soup the clinical benefit of phlegm and blood stasis resistance type lung AECOPD,rich AECOPD combined Chinese and western medicine treatment of clinical thinking,To lay the clinical foundation for further popularization and application of Modified Sanzi Decoction.MethodsA small sample randomized controlled trial was conducted,in which 68 subjects whomet the inclusion criteria and were treated in the pulmonary disease department of Guangzh ou Hospital of Traditional Chinese Medicine from February 2020 to November 2020 were selected and divided into the experimental group and the control group in a ratio of 1:1 accor ding to random number table method.The experimental group was given conventional western medicine treatment on the basis of internal administration of modified sanzi decoction,and the control group was given conventional western medicine treatment only.The course of treatment was 10 days.The changes of efficacy indexes were collected before and after treatment.Finally,SPSS 21.0 statistical software was used to analyze and compare the differences in inflammatory indexes,TCM syndrome score,6MWT,CAT score and clinical efficacy between the two groups before and after treatment,and the clinical efficacy evaluation was obtained.Results1.There were no significant differences in gender composition,age distribution,duration of disease,WBC and PCT,TCM syndrome score,6MWT and CAT score between the two groups before the experiment(P>0.05),indicating comparability.2.Inflammation indicators:After the end of the experiment,WBC and PCT levels of subjects in the two groups decreased compared with before treatment,with statistical significance(P<0.05);The difference between the two groups was significantly lower in the experimental group than in the control group,and the difference was statistically significant(P<0.05).These results indicated that both treatment regimens could reduce the inflammatory response of the subjects,and the experimental group was better than the control group in controlling the inflammatory response.3.TCM syndrome scores:After the end of the experiment,TCM syndrome scores of subjects in both groups decreased compared with before treatment,with statistical significance(P<0.05).The results showed that both treatments could improve the symptoms of cough,expectoration,chest pain,shortness of breath,weakness,stomach and so on.The score difference of the experimental group was greater than that of the control group,and the difference was statistically significant(P<0.05),indicating that the experimental group was more significant in the control of clinical symptoms than the control group.In the comparison of clinical efficacy,the total effective rate and average rank of the experimental group were better than those of the control group,indicating that the clinical effective rate of the experimental group was higher than that of the control group(P<0.05).4.6MWT:After the end of the experiment,the 6MWT of subjects in both groups was higher than that before treatment,and the increase in the experimental group was significantly higher than that in the control group,the difference was statistically significant(P<0.05).The experimental group was better than the control group in restoring the motor function of the subjects.5.CAT score:After the end of the experiment,the CAT score of subjects in both groups was higher than that before treatment,and the increase in the experimental group was greater than that in the control group,the difference was statistically significant(P<0.05).It is believed that the experimental group can improve the daily activities of subjects and improve the quality of life more than the control group.ConclusionThe efficacy of modified sanzi decoction in the treatment of phlegm-stasis type AECO PD is more significant than that of simple western medicine intervention.It can more effect ively control the inflammatory response of patients,reduce the clinical symptoms and signs of acute aggravation,improve exercise endurance,improve daily activities,and have no adverse reactions.